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London - Sloane Stephens became Wimbledon's first big-name casualty this year as the world number four crashed to a shock 6-1, 6-3 defeat against Croatia's Donna Vekic on Monday.
Stephens was expected to mount a strong challenge at the All England Club after winning her maiden Grand Slam crown at the 2017 US Open and finishing as French Open runner-up last month.
But the 25-year-old American, who has been in fine form since returning from foot surgery last year, had only gone past the Wimbledon third round once in six previous visits.
She was beaten in the first round last year and maintained her poor record on grass with another limp display against world number 55 Vekic on Court One.
Vekic, who sealed the upset on her fourth match point, faces Slovakia's Viktoria Kuzmova or Sweden's Rebecca Peterson in the second round.
Wimbledon results on Monday, the first day of the 2018 championships (x denotes seeded player):
Men
1st round
Roger Federer (SUI x1) bt Dusan Lajovic (SRB) 6-1, 6-3, 6-4
Ivo Karlovic (CRO) bt Mikhail Youzhny (RUS) 4-6, 7-5, 7-6 (9/7), 6-3
Jan-Lennard Struff (GER) bt Leonardo Mayer (ARG x32) 3-6, 6-7 (5/7), 7-6 (7/5), 7-6 (7/5), 6-1
Adrian Mannarino (FRA x22) bt Christian Garin (CHI) 6-3, 1-6, 7-6 (7/4), 6-2
Ryan Harrison (USA) bt Roberto Carballes (ESP) 6-1, 6-4, 6-2
Guillermo Garcia-Lpez (ESP) bt Gasto Elias (POR) 6-2, 6-4, 6-2
Daniil Medvedev (RUS) bt Borna Coric (CRO x16) 7-6 (8/6), 6-2, 6-2
Sam Querrey (USA x11) bt Jordan Thompson (AUS) 6-2, 6-4, 6-3
Sergiy Stakhovsky (UKR) bt Joao Sousa (POR) 6-3, 6-3, 5-7, 1-6, 6-4
Gael Monfils (FRA) bt Richard Gasquet (FRA x23) 7-6 (8/6), 7-5, 6-4
Philipp Kohlschreiber (GER x25) bt Evgeny Donskoy (RUS) 6-2, 6-4, 7-5
Gilles Muller (LUX) bt Michael Mmoh (USA) 7-5, 4-6, 7-6 (9/7), 3-6, 6-1
Andreas Seppi (ITA) bt John-Patrick Smith (AUS) 6-2, 6-4, 6-1
Kevin Anderson (RSA x8) bt Norbert Gombos (SVK) 6-3, 6-4, 6-4
Marin Cilic (CRO x3) bt Yoshihito Nishioka (JPN) 6-1, 6-4, 6-4
Guido Pella (ARG) bt Jason Kubler (AUS) 6-4, 7-5, 4-6, 7-6 (7/3)
Mackenzie McDonald (USA) bt Ricardas Berankis (LTU) 4-6, 7-6 (8/6), 6-3, 7-6 (8/6)
Nicolas Jarry (CHI) bt Filip Krajinovic (SRB x28) 6-3, 3-6, 7-6 (7/5), 6-4
Lucas Pouille (FRA x17) bt Denis Kudla (USA) 6-3, 6-3, 2-6, 6-3
Dennis Novak (AUT) bt Peter Polansky (CAN) 6-2, 6-3, 7-6 (9/7)
John Millman (AUS) bt Stefano Travaglia (ITA) 6-7 (6/8), 6-3, 7-5, 6-2
Milos Raonic (CAN x13) bt Liam Broady (GBR) 7-5, 6-0, 6-1
John Isner (USA x9) bt Yannick Maden (GER) 6-2, 7-6 (7/4), 7-5
Stefanos Tsitsipas (GRE x31) bt Gregoire Barrere (FRA) 6-3, 6-4, 6-7 (3/7), 7-5
Jared Donaldson (USA) bt Malek Jaziri (TUN) 7-6 (7/5), 6-3, 6-1
Thomas Fabbiano (ITA) bt Yuki Bhambri (IND) 2-6, 6-3, 6-3, 6-2
Stan Wawrinka (SUI) bt Grigor Dimitrov (BUL x6) 1-6, 7-6 (7/3), 7-6 (7/5), 6-4
Women
1st round
Karolina Pliskova (CZE x7) bt Harriet Dart (GBR) 7-6 (7/2), 2-6, 6-1
Victoria Azarenka (BLR) bt Ekaterina Alexandrova (RUS) 7-6 (7/4), 6-3
Katie Swan (GBR) bt Irina Camelia Begu (ROM) 6-2, 6-2
Kiki Bertens (NED x20) bt Barbora Stefkova (CZE) 6-3, 6-2
Anna Blinkova (RUS) bt Wang Yafan (CHN) 6-7 (4/7), 6-4, 6-4
Alexandra Dulgheru (ROM) bt Kristyna Pliskova (CZE) 6-4, 1-6, 6-2
Venus Williams (USA x9) bt Johanna Larsson (SWE) 6-7 (3/7), 6-2, 6-1
Lesia Tsurenko (UKR) bt Timea Babos (HUN) 7-5, 6-2
Andrea Petkovic (GER) bt Zhang Shuai (CHN x31) 6-4, 4-6, 6-2
Yanina Wickmayer (BEL) bt Mona Barthel (GER) 7-5, 6-4
Rebecca Peterson (SWE) bt Viktoria Kuzmova (SVK) 7-6 (7/3), 7-6 (11/9)
Donna Vekic (CRO) bt Sloane Stephens (USA x4) 6-1, 6-3
Kristina Mladenovic (FRA) bt Anna Karolina Schmiedlova (SVK) 5-7, 6-2, 6-2
Serena Williams (USA x25) bt Arantxa Rus (NED) 7-5, 6-3
Sorana Cirstea (ROM) bt Magdalena Rybarikova (SVK x19) 7-5, 6-3
Evgeniya Rodina (RUS) bt Antonia Lottner (GER) 3-6, 7-5, 6-4
Luksika Kumkhum (THA) bt Bernarda Pera (USA) 4-6, 6-2, 6-3
Madison Keys (USA x10) bt Ajla Tomljanovic (AUS) 6-4, 6-2
Madison Brengle (USA) bt Aleksandra Krunic (SRB) 2-6, 6-3, 6-3
Camila Giorgi (ITA) bt Anastasija Sevastova (LAT x21) 6-1, 2-6, 6-4
Ekaterina Makarova (RUS) bt Petra Martic (CRO) 7-6 (7/0), 2-6, 6-3
Caroline Wozniacki (DEN x2) bt Varvara Lepchenko (USA) 6-0, 6-3
