London - American ninth seed John Isner reached his first Wimbledon quarter-final at the 10th attempt on Monday with a 6-4, 7-6 (10/8), 7-6 (7/4) win over Greek teenager Stefanos Tsitsipas.
Isner, 33, will be playing in his first quarter-final at the majors since the 2011 US Open when he faces former Wimbledon finalist Milos Raonic for a semi-final spot on Wednesday.
Tsitsipas was bidding to become the first ever Greek player - man or woman - to reach the last-eight at a Grand Slam.
Wimbledon results on Monday, the seventh day of the 2018 championships (x denotes seeded player):
Men
Fourth round
Roger Federer (SUI x1) bt Adrian Mannarino (FRA x22) 6-0, 7-5, 6-4
Kevin Anderson (RSA x8) bt Gael Monfils (FRA) 7-6 (7/4), 7-6 (7/2), 5-7, 7-6 (7/4)
Milos Raonic (CAN x13) bt Mackenzie McDonald (USA) 6-3, 6-4, 6-7 (5/7), 6-2
John Isner (USA x9) bt Stefanos Tsitsipas (GRE x31) 6-4, 7-6 (10/8), 7-6 (7/4)
Novak Djokovic (SRB x12) bt Karen Khachanov (RUS) 6-4, 6-2, 6-2
Kei Nishikori (JPN x24) bt Ernests Gulbis (LAT) 4-6, 7-6 (7/5), 7-6 (12/10), 6-1
Rafael Nadal (ESP x2) bt Jiri Vesely (CZE) 6-3, 6-3, 6-4
Suspended due to darkness:
Juan Martin del Potro (ARG x5) leads Gilles Simon (FRA) 7-6 (7/1), 7-6 (7.5), 5-7
Women
Fourth round
Dominika Cibulkova (SVK) bt Hsieh Su-Wei (TPE) 6-4, 6-1
Jelena Ostapenko (LAT x12) bt Aliaksandra Sasnovich (BLR) 7-6 (7/4), 6-0
Daria Kasatkina (RUS x14) bt Alison Van Uytvanck (BEL) 6-7 (6/8), 6-3, 6-2
Angelique Kerber (GER x11) bt Belinda Bencic (SUI) 6-3, 7-6 (7/5)
Kiki Bertens (NED x20) bt Karolina Pliskova (CZE x7) 6-3, 7-6 (7/1)
Julia Goerges (GER x13) bt Donna Vekic (CRO) 6-3, 6-2
Serena Williams (USA x25) bt Evgeniya Rodina (RUS) 6-2, 6-2
Camila Giorgi (ITA) bt Ekaterina Makarova (RUS) 6-3, 6-4