London - Kiki Bertens knocked out the last top 10 seed in the women's singles at Wimbledon as the Dutch world No 20 stunned Karolina Pliskova with a 6-3, 7-6 (7/1) victory in the fourth round on Monday.
Bertens followed her shock third round success against five-time Wimbledon champion Venus Williams by claiming the scalp of Czech seventh seed Pliskova.
The exit of former world number one Pliskova came after the women's draw was blown wide open by surprise defeats earlier in the tournament for Maria Sharapova, Petra Kvitova, Caroline Wozniacki, Simona Halep and Sloane Stephens.
Germany's Angelique Kerber, seeded 11th, is the top ranked player remaining.
But the title favourite is seven-time champion Serena Williams, seeded 25th after her lengthy maternity leave, and due to face Russian qualifier - and fellow mother - Evgeniya Rodina later on Monday.
Bertens, a French Open semi-finalist in 2016, is into the Wimbledon quarter-finals for the first time.
The 26-year-old faces German 13th seed Julia Goerges or Croatian world No 55 Donna Vekic on Tuesday.
Bertens, who was contemplating retirement last year after losing her enthusiasm for the sport, is the first Dutch woman to reach the Wimbledon quarter-finals since Michaella Krajicek in 2007.
Wimbledon results on Monday, the seventh day of the 2018 championships (x denotes seeded player):
Roger Federer (SUI x1) bt Adrian Mannarino (FRA x22) 6-0, 7-5, 6-4
Kevin Anderson (RSA x8) bt Gael Monfils (FRA) 7-6 (7/4), 7-6 (7/2), 5-7, 7-6 (7/4)
Milos Raonic (CAN x13) bt Mackenzie McDonald (USA) 6-3, 6-4, 6-7 (5/7), 6-2
John Isner (USA x9) bt Stefanos Tsitsipas (GRE x31) 6-4, 7-6 (10/8), 7-6 (7/4)
Novak Djokovic (SRB x12) bt Karen Khachanov (RUS) 6-4, 6-2, 6-2
Kei Nishikori (JPN x24) bt Ernests Gulbis (LAT) 4-6, 7-6 (7/5), 7-6 (12/10), 6-1
Rafael Nadal (ESP x2) bt Jiri Vesely (CZE) 6-3, 6-3, 6-4
Suspended due to darkness:
Juan Martin del Potro (ARG x5) leads Gilles Simon (FRA) 7-6 (7/1), 7-6 (7.5), 5-7
Dominika Cibulkova (SVK) bt Hsieh Su-Wei (TPE) 6-4, 6-1
Jelena Ostapenko (LAT x12) bt Aliaksandra Sasnovich (BLR) 7-6 (7/4), 6-0
Daria Kasatkina (RUS x14) bt Alison Van Uytvanck (BEL) 6-7 (6/8), 6-3, 6-2
Angelique Kerber (GER x11) bt Belinda Bencic (SUI) 6-3, 7-6 (7/5)
Kiki Bertens (NED x20) bt Karolina Pliskova (CZE x7) 6-3, 7-6 (7/1)
Julia Goerges (GER x13) bt Donna Vekic (CRO) 6-3, 6-2
Serena Williams (USA x25) bt Evgeniya Rodina (RUS) 6-2, 6-2
Camila Giorgi (ITA) bt Ekaterina Makarova (RUS) 6-3, 6-4