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Ferrer advanced with a scrappy 6-3, 3-6, 7-6 (4), 7-5 win in a match originally scheduled for Thursday but pushed back because of rain.
He will next face No. 26 Alexandr Dolgopolov.
After losing in the French Open final to Rafael Nadal, Ferrer has struggled to switch from clay to grass.
As the defending champion he lost in the first round at Rosmalen in his warmup tournament for Wimbledon and then was taken to four sets in his first-round match here.
Ferrer said "I feel better than in the first day and last week.
"I'm improving my game on these courts."
Ferrer's best result at Wimbledon was reaching the quarter-finals last year.
Results from the fifth day of Wimbledo (x denotes seeded player):
Men's singles:
Third round:
Jerzy Janowicz (POL x24) bt Nicolas Almagro (ESP x15) 7-6 (8/6), 6-3, 6-4
Jurgen Melzer (AUT) bt Sergiy Stakhovsky (UKR) 6-2, 2-6, 7-5, 6-3
Andy Murray (GBR x2) bt Tommy Robredo (ESP x32) 6-2, 6-4, 7-5
Second round:
Jeremy Chardy (FRA x28) bt Jan-Lennard Struff (GER) 6-2, 5-7, 7-6 (8/6), 7-6 (7/4)
Tommy Haas (GER x13) bt Jimmy Wang (TPE) 6-3, 6-2, 7-5
David Ferrer (ESP x4) bt Roberto Bautista (ESP) 6-3, 3-6, 7-6 (7/4), 7-5
Alexandr Dolgopolov (UKR x26) bt Santiago Giraldo (COL) 6-4, 7-5, 6-3
Grega Zemlja (SLO) bt Grigor Dimitrov (BUL x29) 3-6, 7-6 (7/4), 3-6, 6-4, 11-9
Women's singles:
Third round:
Marion Bartoli (FRA x15) bt Camila Giorgi (ITA) 6-4, 7-5
Karin Knapp (ITA) bt Michelle Larcher de Brito (POR) 7-5, 6-2
Carla Suarez Navarro(ESP x19) bt Eugenie Bouchard (CAN) 7-5, 6-2
Kirsten Flipkens (BEL x20) bt Vesna Doloncs (SRB) 6-4, 6-2
Flavia Pennetta (ITA) bt Alize Cornet (FRA x29) 0-6, 7-6 (7/4), 6-2
Laura Robson (GBR) bt Mariana Duque-Marino (COL) 6-4, 6-1
Alison Riske (USA) bt Urszula Radwanska (POL) 4-6, 6-3, 6-4
Kaia Kanepi (EST) bt Angelique Kerber (GER x7) 3-6, 7-6 (8/6), 6-3
