New York - Canadian qualifier Denis Shapovalov became the youngest player to reach the US Open last 16 since 1989 on Friday when British opponent Kyle Edmund retired from their third-round match with a neck injury.
Shapovalov, 18, was ahead 3-6, 6-3, 6-3, 1-0 when Edmund quit. Shapovalov became the youngest man in the fourth round since 17-year-old Michael Chang in 1989.
He will play Spain's Pablo Carreno Busta for a place in the quarter-finals.
Results from day 5 of the US Open on Friday (x denotes seeding):
Men
Third round
Sam Querrey (USA x17) bt Radu Albot (MDA) 4-6, 6-2, 6-4, 6-4
Mischa Zverev (GER x23) bt John Isner (USA x10) 6-4, 6-3, 7-6 (7/5)
Paolo Lorenzi (ITA) bt Thomas Fabbiano (ITA) 6-2, 6-4, 6-4
Kevin Anderson (RSA x28) bt Borna Coric (CRO) 6-4, 6-3, 6-2
Denis Shapovalov (CAN) bt Kyle Edmund (GBR) 3-6, 6-3, 6-3, 1-0 - retired
Pablo Carreño-Busta (ESP x12) bt Nicolas Mahut (FRA) 6-3, 6-4, 6-3
Lucas Pouille (FRA x16) bt Mikhail Kukushkin (KAZ) 2-6, 6-3, 6-4, 6-4
Diego Schwartzman (ARG) bt Marin Cilic (CRO x5) 4-6, 7-5, 7-5, 6-4
Women
Third round
Carla Suárez Navarro (ESP) bt Ekaterina Makarova (RUS) 6-1, 3-6, 6-3
Venus Williams (USA x9) bt Maria Sakkari (GRE) 6-3, 6-4
Petra Kvitova (CZE x13) bt Caroline Garcia (FRA x18) 6-0, 6-4
Garbiñe Muguruza (ESP x3) bt Magdaléna Rybáriková (SVK x31) 6-1, 6-1
Julia Goerges (GER) bt Aleksandra Krunic (SRB) 6-3, 6-3
Sloane Stephens (USA) bt Ashleigh Barty (AUS) 6-2, 6-4
Anastasija Sevastova (LAT x16) bt Donna Vekic (CRO) 6-2, 6-3
Maria Sharapova (RUS) bt Sofia Kenin (USA) 7-5, 6-2