Sao Paolo - Sixth-seeded Jaume Munar and No 7 seed Juan Ignacio Londero advanced at the Brazil Open on Tuesday.
Munar, of Spain, beat Brazilian Pedro Sakamoto 6-3, 6-2, while Argentina's Londero - who won the Cordoba Open earlier this month - topped Italy's Paolo Lorenzi 7-6 (7/3), 6-1.
Munar will face Chile's Christian Garin in the round of 16 at the clay-court tournament, while Londero will play Bolivia's Hugo Dellien.
Dellien, a 25-year-old Bolivian, beat Spain's Pedro Martinez Portero 6-1, 6-2. Dellien reached the quarter-finals of the Rio Open last week.
Also on Tuesday, Spain's Albert Ramos Vinolas beat Argentina's Facundo Bagnis 6-1, 6-3.
Brazil's Thiago Seyboth Wild eliminated Sweden's Elias Ymer 6-3, 4-6, 6-2.
Norway's Casper Ruud advanced with a 6-3, 6-4 victory over local favorite Thiago Monteiro.