Lille - Benoit Paire and Lucas Pouille will play for France in the opening singles against Spain in the Davis Cup semi-finals.
Making his debut in the competition, Paire will take on 21st-ranked Pablo Carreno Busta on a hard court in the northern city of Lille.
The 19th-ranked Pouille will then play Roberto Bautista Agut.
Julien Benneteau and Nicolas Mahut are set to face Marcel Granollers and Feliciano Lopez in Saturday's doubles.
Spain is without top-ranked Rafael Nadal, who was ruled out because of the right knee injury that forced him to retire from his semi-final match against Juan Martin del Potro last week at the US Open.
The countries are meeting for the ninth time, with Spain leading 6-2.
Matches will be played on an indoor court at the 27 500-capacity Pierre Mauroy Stadium, with the roof closed. France won its 10th Davis Cup title last year in the same venue, beating Belgium 3-2.
Croatia is hosting the United States in the other semi-final series.