Cape Town - South Africa’s Kevin Anderson was knocked out of the Japan Open on Wednesday after losing his second round encounter to American Ryan Harrison.
The unseeded Harrison prevailed 6-3, 1-6, 7-6 (7/2) over the fifth-seeded Anderson.
Anderson, the world No 16, had earlier in the week defeated Frenchman Gilles Simon in straight sets but looked out of sorts on Wednesday.
It was Anderson’s first tournament since his run to the US Open final last month, where he lost to world No 1 Rafael Nadal.
Results of singles matches at the Japan Open men's tennis tournament in Tokyo on Wednesday (x denotes seeding):
Adrian Mannarino (FRA) bt Jiri Vesely (CZE) 6-3, 6-2
Diego Schwartzman (ARG x8) bt Bernard Tomic (AUS) 6-3, 6-1
Ryan Harrison (USA) bt Kevin Anderson (RSA x5) 6-3, 1-6, 7-6 (7/2)
David Goffin (BEL x4) bt Feliciano Lopez (ESP) 7-5, 6-1
Oleksandr Dolgopolov (UKR) bt Daniil Medvedev (RUS) 6-1, 6-2