Rosmalen - Second-seeded Stanislas Wawrinka beat Paolo Lorenzi 6-3, 7-6 (8) Wednesday to advance to the quarterfinals of the Topshelf Open on the grass courts of Rosmalen.
The Italian never managed to seriously threaten Wawrinka's serve until the 12th game of the second set, when he broke the Swiss to force a tiebreak.
He then fought off three match points before finally succumbing 10-8 to the No. 10-ranked Wawrinka, who next plays Jeremy Chardy.
Second-seeded Dominika Cibulkova reached the women's quarterfinals by coming from a set down to beat Anabel Medina Garrigues 2-6, 6-4, 6-3.
Earlier, the last two remaining Dutch players lost their second-round matches. Kirsten Flipkens beat Michaella Krajiceck in two hard-fought sets 7-6 (6), 7-6 (3), and Evgeny Donskoy overcame Robin Haase 6-4, 7-5.
Results from day four of the 's-Hertogenbosch ATP/WTA (x denotes seeding):
Guillermo Garca-Lopez (ESP) bt Daniel Brands (GER) 7-6 (9/7), 6-2
Stanislas Wawrinka (SUI x2) bt Paolo Lorenzi (ITA) 6-3, 7-6 (10/8)
Jeremy Chardy (FRA x5) bt Marius Copil (ROM) 7-5, 6-4
Roberto Bautista (ESP) bt Carlos Berlocq (ARG) 6-2, 6-3
Evgeny Donskoy (RUS) bt Robin Haase (NED) 6-4, 7-5
Nicolas Mahut (FRA) bt Andrey Kuznetsov (RUS) 6-2, 6-4
Jan Hernych (CZE) bt Michael Llodra (FRA) 6-7 (5/7), 6-4, 7-5
Lesya Tsurenko (UKR) bt Stefanie Vogele (SUI) 6-1, 7-6 (7/4)
Kirsten Flipkens (BEL x4) bt Michalla Krajicek (NED) 7-6 (8/6), 7-6 (7/3)
Garbine Muguruza (ESP) bt Lauren Davis (USA) 6-2, 6-0
Dominika Cibulkova (SVK x2) bt Anabel Medina Garrigues (ESP) 2-6, 6-4, 6-3