Bucharest - Fifth-seeded Guillermo Garcia-Lopez has lost only five service points in beating qualifier Lorenzo Giustino 6-2, 6-0 at the Nastase Tiriac Trophy on Tuesday.
The 2013 champion from Spain will next face Marcos Baghdatis of Cyprus.
Baghdatis beat Steve Darcis 6-4, 6-2 in the second round.
Also, eighth-seeded Simone Bolelli saved five of seven break points to beat Andrey Golubev 7-6 (3), 6-4, and wild-card entry Janko Tipsarevic defeated qualifier Thomas Fabbiano 6-4, 6-3.
A quarterfinalist two years ago, Tipsarevic was playing in his third match since October 2013. He recently returned after a persistent foot injury.
Results on the second day of the Bucharest ATP tennis tournament on Tuesday (x denoted seeding):
Guillermo Garca-Lopez (ESP x5) bt Lorenzo Giustino (ITA) 6-2, 6-0
Marcos Baghdatis (CYP) bt Steve Darcis (BEL) 6-4, 6-2
Dusan Lajovic (SRB) bt Jurgen Zopp (EST) 7-5, 6-1
Simone Bolelli (ITA) bt Andrey Golubev (KAZ) 7-6 (7/3), 6-4
Andreas Haider-Maurer (AUT) bt Ivan Dodig (CRO) 7-5, 0-6, 6-4