Cape Town - Bidvest Wits will be favourites to advance to the next round when travelling to Maritzburg United in the first round of the Telkom Knockout on Friday.
The Clever Boys have made a strong start to the league season having won five of their first six games to sit in second place on the Absa Premiership table.
Gavin Hunt's charges also have a good record over the years when playing at the Harry Gwala Stadium that has seen them lose just three of their previous 25 meetings in all competitions at the venue in KwaZulu-Natal.
It is also a repeat of last season's Telkom Knockout fixture when Wits knocked Maritzburg out of the cup with a 2-1 victory.
The Team of Choice have not had the strongest start to the current campaign as they have won twice in seven matches to sit in 11th place on the log.
Eric Tinkler's men might be better off concentrating on moving up the league table but midfielder Bandile Shandu is adamant that they will take the cup game seriously.
"We want to go as far as we can in this Cup, but we must take it one game at a time," Shandu said.
"We are looking at Wits right now and this is a very important game."
The match kicks off is at 20:00 on Friday at the Harry Gwala Stadium.
- TeamTalk Media