Cape Town - Kaizer Chiefs and Orlando Pirates will meet in the Telkom Knockout quarter-finals after the draw for the last eight was completed on Tuesday evening.
Kaizer Chiefs, who beat Cape Town City in a last 16 fixture on Saturday, will have home ground advantage.
In other fixtures, SuperSport United take on Golden Arrows, Chippa United are at home to Mamelodi Sundowns and Maritzburg United will face Highlands Park.
The dates, venues and kick-off times will be confirmed in due course.