Cape Town - Defending Telkom Knockout champions Cape Town City FC have been drawn against Baroka FC while Soweto giants Kaizer Chiefs face AmaZulu in the last 16 of this year's tournament.
Pitso Mosimane's Mamelodi Sundowns will travel to the Eastern Cape for a clash against Chippa United.
Orlando Pirates take on high-flying Golden Arrows in KwaZulu-Natal with Wits welcoming Free State Stars to the Bidvest Stadium.
Bloemfontein Celtic will hope to overcome the newly crowned MTN8 champions SuperSport United in perhaps the round's stand-out fixture.
Official dates and venues for each fixture will be announced in due course.
Baroka FC v Cape Town City FC
Chippa United v Mamelodi Sundowns
Bloemfontein Celtic v SuperSport United
Polokwane City v Ajax Cape Town
Kaizer Chiefs v AmaZulu
Bidvest Wits v Free State Stars
Maritzburg United v Platinum Stars
Golden Arrows v Orlando Pirates