"We will all have to remain calm and continue fighting until the last whistle," said Pirates captain Lucky Lekgwathi.
"We, as the players, will do our best to win this match."
A victory over Arrows on Saturday would be enough for the Buccaneers to retain their Premiership crown.
If successful, they would become the fourth team to win back-to-back crowns, while completing a consecutive treble of trophies.
Should Pirates win on Saturday, they would lift six of the eight domestic titles on offer in the last 24 months - the most prolific era in the side's 75 year history.
"Whenever we had a big game a few years back, we would be stressing-out about how the game would unfold," said Lekgwathi.
"Some of the guys would even dream about the game, which was quite disturbing then.
"Now things are a bit different and everyone in camp seems to enjoy it."
Second-placed Moroka Swallows are still in with a shout and should they beat Maritzburg United in Pietermaritzburg, and Pirates either lose or draw, they would win their inaugural championship.
For Pirates winger Daine Klate, the campaign's final fixture against mid-table Abafana Bes'thende is a chance to add a fifth league winner's medal to his mantelpiece.
He warned that Arrows would not make it easy for them.
"They're going into the game with nothing to lose," Klate said.
"We want the three points at all costs to wrap up the title in style."
Third-placed SuperSport United can finish second should they beat Bloemfontein Celtic in Botshabelo and Swallows lose their fixture.
Mamelodi Sundowns, who take on Free State Stars in Atteridgeville, and Kaizer Chiefs, playing AmaZulu at FNB Stadium, can also finish in third place provided other results go their way.
Chiefs interim co-coach Doctor Khumalo said Amakhosi needed a positive finish to a poor campaign this season.
"AmaZulu is a good team," Khumalo said.
"But we aim to finish on a high note, and hopefully build for a better new season."
At the bottom of the table, Santos will be out to avoid a play-off spot when they host already relegated Jomo Cosmos at Athlone Stadium.
Meanwhile, 14th-placed Black Leopards need a win over Ajax Cape Town in Giyani, should Santos be successful in their mission.
If Santos draw or lose to Cosmos, Leopards will remain third from bottom and avoid the relegation play-offs.
In the one other fixture, Platinum Stars host Wits in Rustenburg.
All games kick-off at 15:00.