Majavu, according to the PSL, had been under the impression he could appoint the league body's COO, CFO and head of legal affairs.
The PSL, however, informed Majavu that only the executive committee could make these appointments.
"Majavu held the view that he could not accept this," the PSL said in a statement.
"On this basis, the PSL and Mr Majavu agreed to part ways amicably due to these fundamental differences."
Irvin Khoza, the PSL chairman, said Cambridge Mokanyane would take an acting role as the interim CEO.