Amakhosi play their first home game of the new campaign this week following away ties in the MTN8 and opening round of the PSL last weekend.
"We are delighted to be at home for this game against Sundowns. It is important that we make Soccer City our fortress and make it uncomfortable for teams to dictate terms in our own backyard," the Englishman told the club's official website.
"I am pleased with the preparations for this game. Decisions will be made on the availability of Siboniso (Gaxa) and George Lebese who both have been out due to different injuries."
Chiefs began the new PSL campaign with a resounding 6-0 thrashing of AmaZulu, but Baxter is expecting an entirely different encounter against the Brazilians, who recently conceded three goals in the 3-3 draw against Moroka Swallows in the Wafa Wafa semi-finals.
"We have put the game against AmaZulu behind us and we will focus on Mamelodi Sundowns. They are a good team and have a lot of good players," he said.
"We now have more information on them as compared to the last time we met them at Loftus. We also had an opportunity to watch them this past weekend against Moroka Swallows.
"The players and everyone associated with the Club is excited about the upcoming game. It does not make a difference that we are meeting them for the second time in a space of three weeks. We need to go out there and execute our game plan. We are up for this game.
"The players have responded well to my philosophy from day one and as the Technical Team we are pleased by the hunger they have shown since our first game against Moroka Swallows in the Gauteng Challenge Cup."