Johannesburg - Chad shocked Egypt 1-0 and Algeria came from two goals down to draw 2-2 with Tanzania Saturday in African 2018 World Cup first-leg qualifiers.
Congo Brazzaville won 4-3 in Ethiopia and Botswana used home advantage to beat Mali 2-1 in a game that completed the 20 first-leg fixtures in the second round of qualifying for Russia.
The Chadians triumphed in N'Djamena two months after suffering a 5-1 Africa Cup of Nations drubbing from the Egyptians at the same ground.
Tunisia-based captain Ezechiel N'Douassel won the match with a flying header past Ahmed El Shenaway on 73 minutes at Stade Idriss Mahamat Ouya.
Forced to defend for much of the opening half against twice World Cup qualifiers Egypt, the home side took control after the break and the goal rewarded constant pressure.
The return match is scheduled for Tuesday at the Borg El Arab Stadium on the outskirts of Mediterranean city Alexandria.
Islam Slimani struck twice within four minutes midway through the second half for four-time qualifiers Algeria, who are 109 places above Tanzania on the world rankings.
It was the second dramatic comeback in as many days in East Africa by a highly-ranked visiting team with Senegal coming from two goals down to draw 2-2 in Madagascar.
At Addis Ababa
Ethiopia 3 (Gibeto 41, Fekadu 82, Bekele 90+1) Congo Brazzaville 4 (Bifouma 43, Nguessi 63, Ndinga 75, Binguila 81)
At Dar es Salaam
Tanzania 2 (Maguri 43, Samatta 55) Algeria 2 (Slimani 72, 75)
Chad 1 (N'Douassel 73) Egypt 0
At Francistown, Botswana
Botswana 2 (Gadibolae 14, Mogorosi 23) Mali 1 (Sow 56)
Madagascar 2 (Andriatsima 27, Rakotoharimalala 59) Senegal 2 (Diouf 71, Mane 81)
At Mitsamiouli, Comoros
Comoros 0 Ghana 0
Kenya 1 (Olunga 9) Cape Verde 0
At Sfax, Tunisia
Libya 1 (Saleh 48-pen) Rwanda 0
Note: post-Moamer Kadhafi-era violence prevented fixture being staged in Libya
At Benguela, Angola
Angola 1 (Gelson 2) South Africa 3 (Rantie 14, Gabuza 20, Jali 82-pen)
Niger 0 Cameroon 3 (M'bia 36, Aboubakar 39, Salli 40)
Liberia 0 Ivory Coast 1 (Cyriac 44)
Mauritania 1 (N'Diaye 22) Tunisia 2 (Khazri 62, Chikhaoui 68)
At Lobamba, Swaziland
Swaziland 0 Nigeria 0
Second legs: Nov 14, 15, 17