Cape Town - English Premier League outfit Arsenal will face CSKA Moscow following the UEFA Europa quarter-final draw.
Atletico Madrid will welcome Sporting Lisbon to the Wanda Metropolitano with Serie A side Lazio playing in unfamiliar territory against Austria's FC Salzburg.
Marseille will travel to Germany for a clash against RB Leipzig.
Arsene Wenger's chargers overcame Italian giants AC Milan (winning 5-1 on aggregate) over a two-leg encounter to secure their spot in the next round.
Gunners will need to win the competition if they are to have any chance of playing in the Champions League next season.
Arsenal are currently occupying sixth place (48 points) with Chelsea in fifth (54) and Liverpool (60) in the all important fourth place on the log standings.
Europa League quarter-final draw:
Leipzig v Marseille
Arsenal vs CSKA Moscow
Atletico Madrid vs Sporting Lisbon
Lazio vs FC Salzburg