Leverkusen - Atletico Madrid arrive at Bayer Leverkusen for Wednesday's Champions League last 16, first leg, clash hoping for a sixth straight clean-sheet in Europe, with Mario Mandzukic and Antoine Griezmann hunting more goals.
Between them the pair have already bagged 37 goals this season as the 2014 Champions League finalists look to leave Leverkusen's BayArena with an advantage in the hunt for a quarter-final place.
Former Bayern Munich striker Mandzukic has already shown Pep Guardiola what he is missing in Bavaria by scoring 20 goals, while Griezmann has hit the net 17 times for Atletico this season.
French midfielder Griezmann says Diego Simeone's Madrid need a good start in Leverkusen, just as they had in Saturday's 3-0 home league win over Almeria to stay third in the table.
"We need to keep working and enjoying the games like we are at the moment," said the Frenchman after netting in the 20th and 29th minute following Mandzukic's 13th-minute penalty.
"We need to face all the games the same way, trying to win and coming out flying from the start."
The only casualty for Madrid is midfielder Koke, who will miss the first leg with a hamstring injury having, scored two goals and provided four assists in the group stages.
Olympiacos were the last team to score against Atletico when they enjoyed a 3-2 group stage win in Greece back in September.
Since then, Madrid have scored 12 goals without reply in Europe, including a 5-0 thumping of Malmo and a 4-0 thrashing of Olympiacos in the return leg.
Bayer 04 Leverkusen host Atlético de Madrid at the BayArena on Wednesday. The match kicks off at 21:45.