Cape Town - Ospreys wing Luke Morgan will make his Wales debut against Scotland at Cardiff's Principality Stadium on Saturday.
Morgan, Wales' record try-scorer on the world sevens circuit, returned to Welsh regional side the Ospreys this season after six years playing in the abbreviated format.
Ospreys flanker Dan Lydiate, whose last international appearance was 11 months ago, was recalled to a Wales team announced on Thursday, with veteran lock Alun Wyn Jones captaining a side that contains seven British and Irish Lions Test players.
Elsewhere, Cardiff Blues back Gareth Anscombe is at flyhalf for only his fourth start in the No 10 shirt in 19 Tests while centre Jonathan Davies, the Lions player of the series in their drawn 2017 campaign against New Zealand returns after nearly a year out of Test action with a foot injury.
Because this match falls outside World Rugby's official window for November Tests, foreign clubs are not obliged to release any of their Wales players for Saturday's fixture.
So Wales will be without their English Premiership quartet of Liam Williams, Dan Biggar, Josh Adams and Tomas Francis.
But Gatland, now back with the Wales camp after returning to his native New Zealand last week following the death of his father, will still be fielding a hugely experienced side with nearly 650 caps between them.
"We are excited to kick off our autumn campaign on Saturday and it was great to welcome Warren back yesterday," said Wales assistant coach Rob Howley on Thursday.
"Warren has been in constant dialogue with us over the past week and we have selected a very strong squad for this weekend."
Former Wales and Lions scrumhalf Howley added: "It is great to reward players on form and we are looking forward to seeing Luke make his debut on the wing.
"He has come through the Sevens system, he will bring a point of difference to the squad and it's a great opportunity for him."
Wales, who beat Scotland 34-7 in this year's Six Nations in Cardiff, have not lost at home to the Scots since a 27-22 defeat in 2002 when opposition coach Gregor Townsend was still playing for the Dark Blues.
Both the Scottish Rugby Union, who announced their team on Wednesday, and their Welsh counterparts have been accused of devaluing their annual clash in the Six Nations by taking the unusual step of agreeing to play each other in November.
There were also complaints that spectators had been led into thinking a portion of their ticket money for the Doddie Weir Cup fixture would go towards raising money for the charity of the former Scotland lock, who is suffering from Motor Neurone Disease.
Initially both the SRU and the Welsh Rugby Union said the fixture was designed to "raise awareness" of MND, but on Monday, following a public outcry, both governing bodies announced they would donate a joint six-figure sum "directly from the proceeds of Saturday's fixture" to the My Name's Doddie Foundation.
Teams:
Wales
15 Leigh Halfpenny, 14 George North, 13 Jonathan Davies, 12 Hadleigh Parkes, 11 Luke Morgan, 10 Gareth Anscombe, 9 Gareth Davies, 8 Ross Moriarty, 7 Justin Tipuric, 6 Dan Lydiate, 5 Alun Wyn Jones (c), 4 Cory Hill, 3 Dillon Lewis, 2 Ken Owens, 1 Nicky Smith
Substitutes: 16 Elliot Dee, 17 Rob Evans, 18 Leon Brown, 19 Adam Beard, 20 Aaron Wainwright, 21 Tomos Williams, 22 Jarrod Evans, 23 Steff Evans
Scotland
15 Blair Kinghorn; 14 Tommy Seymour, 13 Huw Jones, 12 Alex Dunbar, 11 Lee Jones; 10 Adam Hastings, 9 Ali Price; 8 Ryan Wilson, 7 Hamish Watson, 6 Jamie Ritchie; 5 Jonny Gray, 4 Ben Toolis; 3 Willem Nel, 2 Stuart McInally (captain), 1 Allan Dell
Substitutes: 16 Fraser Brown, 17 Alex Allan, 18 Simon Berghan, 19 Grant Gilchrist, 20 Matt Fagerson, 21 George Horne, 22 Pete Horne, 23 Darcy Graham