London - Elliot Daly will start England's non-cap international on Sunday against the Barbarians at fullback, with Danny Cipriani having to settle for a place among the replacements.
It is Daly's first start in the No 15 jersey, having made all but one of his previous England appearances on the wing, and the selection sees Mike Brown, the usual incumbent in the position, switch to the left wing.
Cipriani has been overlooked for a starting role despite his return to the senior England squad, with George Ford preferred at flyhalf.
The team for the match at Twickenham is co-captained by Ford and Chris Robshaw, and the latter is joined in the back row by Tom Curry, the Sale openside who appears destined to fill the seven jersey for next month's series against South Africa.
The Barbarians fixture serves as a warm-up for the three-Test series against South Africa that takes place in Johannesburg (June 9), Bloemfontein (June 16) and Cape Town (June 23).
"This is a good young squad and their work ethic has been outstanding over the last two weeks," said England coach Eddie Jones.
"Their application to learn has been very good but they are very young at Test level so this week's match against the Barbarians is a fantastic opportunity for them to step up."
15 Elliot Daly, 14 Jonny May, 13 Henry Trinder, 12 Piers Francis, 11 Mike Brown, 10 George Ford (co-captain), 9 Ben Youngs, 8 Zach Mercer, 7 Tom Curry, 6 Chris Robshaw (co-captain), 5 Joe Launchbury, 4 Elliott Stooke, 3 Kyle Sinckler, 2 Jack Singleton, 1 Joe Marler
Substitutes: 16 George McGuigan, 17 Ellis Genge, 18 Nick Schonert, 19 Josh Beaumont, 20 Mark Wilson, 21 Dan Robson, 22 Danny Cipriani, 23 Denny Solomona
15 Chris Ashton, 14 Josua Tuisova, 13 Semi Radradra, 12 Josh Matavesi, 11 Niyi Adeolokun, 10 Finn Russell, 9 Rhodri Williams, 8 Victor Vito, 7 Justin Tipuric, 6 Juan Martin Fernandez Lobbe (captain), 5 Sitaleki Timani, 4 Ultan Dillane, 3 John Afoa, 2 Benjamin Kayser, 1 Denis Buckley
Substitutes: 16 Tatafu Polota-Nau, 17 Loni Uhila, 18 Ramiro Herrera, 19 Joe Tekori, 20 Nili Latu, 21 Greig Laidlaw, 22 Luke McAlister, 23 Malakai Fekitoa