Kick-off is at 16:00 SA time.
Jérôme Garcès will be the man in the middle, and will be assisted by compatriots Pascal Gauzère and Alexandre Ruiz.
Wales' Gareth Simmonds will be the TMO.
Friday, November 21
Fiji v USA at Stade de la Rabine, Vannes - 20:00
Referee: Johnny Lacey (Ireland)
Assistant referees: Peter Fitzgibbon (Ireland), Gary Conway (Ireland)
Television match official: Iain Ramage (Scotland)
Saturday, November 22
Italy v South Africa at Stadio Euganeo, Padua, Italy - 16:00
Referee: Jérôme Garcès (France)
Assistant referees: Pascal Gauzère (France), Alexandre Ruiz (France)
Television match official: Gareth Simmonds (Wales)
Scotland v Tonga at Rugby Park, Kilmarnock, Scotland - 16:30
Referee: JP Doyle (England)
Assistant referees: Greg Garner (England), Marius Mitrea (Italy)
Television match official: Carlo Damasco (Italy)
Portugal v Namibia at Estadio Nacional Jamor, Lisbon, Portugal - 17:00
Referee: Federico Anselmi (Argentina)
Assistant referees: Giuseppe Vivarini (Italy), Vlad Iordachescu (Romania)
Television match official: TBA
Ireland v Australia at Aviva Stadium, Dublin, Ireland - 18:30
Referee: Glen Jackson (New Zealand)
Assistant referees: Nigel Owens (Wales), Mike Fraser (New Zealand)
Television match official: Eric Gauzins (France)
Wales v New Zealand at Millennium Stadium, Cardiff, Wales - 19:30
Referee: Wayne Barnes (England)
Assistant referees: Craig Joubert (South Africa), Luke Pearce (England)
Television match official: Graham Hughes (England)
Romania v Canada at Stadionul National Arcul de Triumf, Bucharest, Romania - 20:30
Referee: Nick Briant (New Zealand)
Assistant referees: Andrew McMenemy (Scotland), Lloyd Linton (Scotland)
Television match official: Geoff Warren (England)
England v Samoa at Twickenham, England - 21:00
Referee: Jaco Peyper (South Africa)
Assistant referees: Mathieu Raynal (France), Dudley Phillips (Ireland)
Television match official: Simon McDowell (Ireland)
France v Argentina at Stade de France, Paris, France - 22:00
Referee: George Clancy (Ireland)
Assistant referees: Steve Walsh (Australia), Stuart Berry (South Africa)
Television match official: Jim Yuille (Scotland)
Sunday, November 23
Georgia v Japan at Mikheil Meshki Stadium, Tbilisi, Georgia
Referee: Romain Poite (France)
Assistant referees: Ian Davies (Wales), TBA (France)
Television match official: Stefano Pennè (Italy)