Edinburgh - Scotland coach Gregor Townsend recalled back row Hamish Watson for Saturday's Calcutta Cup clash away to England as he made six changes to his starting side.
The Scots will hope to finish the Six Nations by retaining the Calcutta Cup with just their second win of the Championship following last week's 18-11 loss to leaders Wales at Murrayfield - a match where Watson impressed off the bench.
Townsend had also recalled Watson's fellow back row forward Sam Skinner as well as fullback Sean Maitland, who plays his club rugby for English champions Saracens.
Wing Byron McGuigan, centre Sam Johnson and lock Ben Toolis have been also brought in to face title-chasing England.
The injured trio of Tommy Seymour, Blair Kinghorn and Jamie Ritchie have dropped out, as has Peter Horne, with Josh Strauss and Jonny Gray moved to the bench.
Scotland travel to London on a run of three straight defeats and they have not beaten England at Twickenham since 1983.
This is part of a dire record on the road that, excluding matches involving Italy, has yielded just two Scotland away wins since the advent of the Six as opposed to Five Nations in 2000 - against Wales in 2002 and Ireland in 2010.
Teams:
England
15 Elliot Daly, 14 Jack Nowell, 13 Henry Slade, 12 Manu Tuilagi, 11 Jonny May, 10 Owen Farrell (captain), 9 Ben Youngs, 8 Billy Vunipola, 7 Tom Curry, 6 Mark Wilson;, 5George Kruis, 4 Joe Launchbury, 3 Kyle Sinckler, 2 Jamie George, 1 Ellis Genge
Substitutes: 16 Luke Cowan-Dickie, 17 Ellis Genge, 18 Dan Cole, 19 Brad Shields, 20 Nathan Hughes, 21 Ben Spencer, 21 George Ford, 23 Ben Te'o
Scotland
15 Sean Maitland; 14 Darcy Graham, 13 Nick Grigg, 12 Sam Johnson, 11 Byron McGuigan; 10 Finn Russell, 9 Ali Price; 8 Magnus Bradbury, 7 Hamish Watson, 6 Sam Skinner; 5 Grant Gilchrist, 4 Ben Toolis; 3 Willem Nel, 2 Stuart McInally (capt), 1 Allan Dell
Substitutes: 16 Fraser Brown, 17 Gordon Reid, 18 Simon Berghan, 19 Jonny Gray, 20 Josh Strauss, 21 Greig Laidlaw, 22 Adam Hastings, 23 Chris Harris