Vence - French rider Rudy Molard of Groupama-FDJ won the sixth stage of the Paris-Nice on Friday in a finish at Vence marked by the crash and withdrawal of Team Sky leader Dutchman Wout Poels.
Spaniard Luis Leon Sanchez of Astana kept the leader's yellow jersey with two days left.
Molard attacked 1 400m from the finish and pulled away on the final climb to finish two seconds ahead of the group of a powerful group that was led in by Belgian Tim Wellens (Lotto-Soudal) with Frenchman Julian Alaphilippe (Quick Step) third.
Molard scored the fourth French victory in the six days of the race.
"The French are doing well in this Paris-Nice," Molard said. "There are two days left and Alaphilippe is well placed in the general."
At 28, Molard won a stage in a World Tour event for the first time. He is based in nearby Antibes and was able to call on local knowledge.
"I live a 30-minute bike ride away, I've been here dozens of times, these are my training routes,", Molard said.
Poels, who was second overall crashed on the descent of La Colle-sur-Loup, less than 10 kilometres from the finish. He was later diagnosed with a fractured left collarbone.
In the overall classification, Sanchez leads Alaphilippe by 22.
There were two notable casualties before the stage began. Sprinter Nacer Bouhanni, a Frenchman tweeted that he was dropping out because he was ill and John Degenkold, a German with Trek-Sagafredo, said he had bronchitis.
Saturday's 175-kilometre seventh stage ends with a 16.3-kilometre climb to the ski resort of Valdeblore La Colmiane.
Stage six results:
1. Rudy Molard (FRA/Groupama-FDJ), 4hrs 40:05sec, 2. Tim Wellens (BEL/LOT) at 2sec, 3. Julian Alaphilippe (FRA/QST) s.t., 4. Luis Leon Sanchez (ESP/AST) s.t., 5. Sam Oomen (NED/SUN) s.t.