Madrid - Ireland's Dan Martin and American Tejay van Garderen were both forced to withdraw from Spain's Vuelta on Saturday after being caught up in a big crash on the eighth stage, their teams have confirmed.
Both came off their bikes on the first of two steep descents with just under 50 kilometres to go on the 182.5km stage from Puebla de Don Fadrique to Murcia.
Martin was lying third in the overall classification with Van Garderen back in 16th.
"We can confirm that Dan Martin has withdrawn from #LV2015 following a crash. Has been taken to the hospital," Martin's Cannondale-Garmin team confirmed on their official Twitter feed.
"#LV2015Stage 8: BMC Racing Team's @tejay_van has withdrawn (injuries from a crash)," BMC also confirmed via Twitter.
One of the favourites for the stage, France's Nacer Bouhanni, also had to withdraw due to injuries suffered in the crash.