Nice - Belgium's Thomas de Gendt won the seventh and penultimate stage of the Paris-Nice on Saturday with a lead of more than six minutes over Estonia's Rein Taaramae and nine minutes over the peloton.
Bradley Wiggins retained the race leader's yellow jersey, on the eve of Sunday's 9.6km uphill time trial from Nice to the Col d'Eze, putting him on course to become the race's first British winner since Tom Simpson in 1967.
At 219.5km, Saturday's stage from Sisteron to Nice was the longest of the race.
Vacansoleil rider De Gendt and Cofidis' Taaramae broke from the peloton in the 48th kilometre and stretched their advantage to almost 13 minutes.
Fifty-six kilometres from the finishing line, De Gendt outdistanced the Estonian as they neared the summit of the Col de Vence, and pulled further ahead as they began the long ride down into Nice.
De Gendt's win was the third Belgian victory in the Paris-Nice after Tom Boonen's in Orleans and Gianni Meersman's in Rodez.
It likewise marked a trio of honours for Dutch team Vacansoleil, following Swede Gustav Larsson's victory in the time trial at Saint-Remy-les-Chevreuse and Dutchman Lieuwe Westra's win at Mende.
The day was miserable for American Levi Leipheimer, of Omega Pharma, who had started the day third in the overall standings but lost his podium berth.
Leipheimer fell twice, and then a third time 20km from the finish after crashing into a police motorbike which had stopped in a bend to protect another grounded rider.
He battled to catch up the peloton, but finished seven minutes behind them.
The stage left Wiggins with a six-second lead on Westra, who could pull off a surprise on Sunday, having come eighth in the world time trial championships in 2011.
Spaniard Alejandro Valverde, meanwhile, stood 18 seconds behind.
Aside from having Westra snapping at his heels, Wiggins will also have to steer clear of the virus that has ripped through the peloton and forced his German team-mate Christian Knees.
Results from the seventh stage of Paris-Nice, held over 219.5km between Sisteron and Nice:
Stage
1. Thomas De Gendt (BEL/VAC) 5hr 11min 48sec
2. Rein Taaramae (EST/COF) at 6min 18sec
3. John Degenkolb (GER/PRO) at 9min 24sec
4. Greg Henderson (NZL/LTB) same time
5. Thor Hushovd (NOR/BMC) s.t.
6. Jose Joaquin Rojas (ESP/MOV) s.t.
7. Romain Feillu (FRA/VAC) s.t.
8. Simon Clarke (AUS/GEC) s.t.
9. Xavier Florencio (ESP/KAT) s.t.
10. Grega Bole (SLO/LAM) s.t.
General classification
1. Bradley Wiggins (GBR/SKY) 27hr 53min 04sec
2. Lieuwe Westra (NED/VAC) at 06secs
3. Alejandro Valverde (ESP/MOV) 18
4. Simon Spilak (SLO/KAT) 37
5. Tejay Van Garderen (USA/BMC) 39
6. Maxime Monfort (BEL/RSH) 46
7. Arnold Jeannesson (FRA/FDJ) 1:06
8. Sylvain Chavanel (FRA/OPQ) 1:16
9. Robert Kiserlovski (CRO/AST) 1:21
10. Angel Vicioso (ESP/KAT) 2:24
Selected:
39. Levi Leipheimer (USA/OPQ) 7:36
Bradley Wiggins retained the race leader's yellow jersey, on the eve of Sunday's 9.6km uphill time trial from Nice to the Col d'Eze, putting him on course to become the race's first British winner since Tom Simpson in 1967.
At 219.5km, Saturday's stage from Sisteron to Nice was the longest of the race.
Vacansoleil rider De Gendt and Cofidis' Taaramae broke from the peloton in the 48th kilometre and stretched their advantage to almost 13 minutes.
Fifty-six kilometres from the finishing line, De Gendt outdistanced the Estonian as they neared the summit of the Col de Vence, and pulled further ahead as they began the long ride down into Nice.
De Gendt's win was the third Belgian victory in the Paris-Nice after Tom Boonen's in Orleans and Gianni Meersman's in Rodez.
It likewise marked a trio of honours for Dutch team Vacansoleil, following Swede Gustav Larsson's victory in the time trial at Saint-Remy-les-Chevreuse and Dutchman Lieuwe Westra's win at Mende.
The day was miserable for American Levi Leipheimer, of Omega Pharma, who had started the day third in the overall standings but lost his podium berth.
Leipheimer fell twice, and then a third time 20km from the finish after crashing into a police motorbike which had stopped in a bend to protect another grounded rider.
He battled to catch up the peloton, but finished seven minutes behind them.
The stage left Wiggins with a six-second lead on Westra, who could pull off a surprise on Sunday, having come eighth in the world time trial championships in 2011.
Spaniard Alejandro Valverde, meanwhile, stood 18 seconds behind.
Aside from having Westra snapping at his heels, Wiggins will also have to steer clear of the virus that has ripped through the peloton and forced his German team-mate Christian Knees.
Results from the seventh stage of Paris-Nice, held over 219.5km between Sisteron and Nice:
Stage
1. Thomas De Gendt (BEL/VAC) 5hr 11min 48sec
2. Rein Taaramae (EST/COF) at 6min 18sec
3. John Degenkolb (GER/PRO) at 9min 24sec
4. Greg Henderson (NZL/LTB) same time
5. Thor Hushovd (NOR/BMC) s.t.
6. Jose Joaquin Rojas (ESP/MOV) s.t.
7. Romain Feillu (FRA/VAC) s.t.
8. Simon Clarke (AUS/GEC) s.t.
9. Xavier Florencio (ESP/KAT) s.t.
10. Grega Bole (SLO/LAM) s.t.
General classification
1. Bradley Wiggins (GBR/SKY) 27hr 53min 04sec
2. Lieuwe Westra (NED/VAC) at 06secs
3. Alejandro Valverde (ESP/MOV) 18
4. Simon Spilak (SLO/KAT) 37
5. Tejay Van Garderen (USA/BMC) 39
6. Maxime Monfort (BEL/RSH) 46
7. Arnold Jeannesson (FRA/FDJ) 1:06
8. Sylvain Chavanel (FRA/OPQ) 1:16
9. Robert Kiserlovski (CRO/AST) 1:21
10. Angel Vicioso (ESP/KAT) 2:24
Selected:
39. Levi Leipheimer (USA/OPQ) 7:36