Cape Town - Brandon Stone and George Coetzee will represent South Africa at the innovative six-hole GolfSixes Cascais event at Oitavos Dunes from June 7-8.
The opening tie of the 2019 edition will feature Portugal's wildcard team - childhood friends Pedro Figueiredo and Ricardo Gouveia - taking on England's Tom Lewis, the reigning Portugal Masters champion, and Paul Waring.
Joining those two teams in Group A will be Scotland - with 2014 Ryder Cup winner Gallacher joined by his fellow winner on the 2019 Race to Dubai David Law - and they will face an India team featuring S S P Chawrasia and Gaganjeet Bhullar in their opening tussle.
The 2018 champions Team Ireland - Paul Dunne and Gavin Moynihan - will begin their title defence against an England Women's team comprising Meghan MacLaren and Florentyna Parker, who have five Ladies European Tour titles between them.
They are joined in Group B by Sweden's Alexander Björk and Joakim Lagergren and Thailand’s Thongchai Jaidee and Pachara Khongwatmai, who face off in the opening match of their group on Friday morning.
The pick of the matches in Group C will also take place first thing on Friday morning when an Australian team featuring three-time European Tour winner Scott Hend and Wade Ormsby takes on Wales, with 2014 Ryder Cup hero Donaldson joined by Stuart Manley.
France's Mattheiu Pavon and Romain Wattel and a Germany Women's team consisting of 20 year old Esther Henseleit, who enjoyed a strong start to the US Women's Open and another young rising star Laura Fuenfstueck complete Group C.
Group D will see current Scottish Open champion Brandon Stone join George Coetzee in a strong South Africa team, and they will begin with a tough assignment against Spain's Jorge Campillo and Nacho Elvira.
Team Italy will be led by 2010 Ryder Cup star Molinari, who will be joined by exciting young prospect Renato Paratore as they take on Team Denmark - comprising 2018 European Challenge Tour No 1 Joachim B Hansen and Jeff Winther - in the final match of the opening session.
Two more sessions will make up Friday's action and the top two teams in each group will progress to Saturday's quarter-finals, when the knockout drama gets underway. After the semi-finals and a third and fourth place play-off, the winner will be decided on Saturday afternoon in the grand finale.
The exciting two-day tournament is being played over a Friday and Saturday for the first time.