Cape Town - Henry Davids was scheduled to play in the RAM SLAM T20 Challenge semi-final against the Warriors at SuperSport Park on Wednesday.
However, minutes before the toss, Davids popped his knee during a warm-up, which meant the Titans opening batsman would not feature in their all-important knockout game.
According to the Citizen website, with Davids' exclusion it meant that the Titans were short of one player of colour.
The current quota system stipulates that all franchises must field six players of colour in their starting XIs at all times during this season's Ram Slam T20, One-Day Cup and four-day Sunfoil Series.
Three of the six must also be black African players.
The Titans' reserves - Heinrich Klaasen and Shaun von Berg - were not players of colour.
According to the publication, Titans CEO Jacques Faul had immediately contacted Cricket South Africa (CSA) explaining their situation with CSA making a provision for the Pretoria-franchise.
However the Titans will need to submit Davids' medical certificate and a written report to CSA's transformation manager, Max Jordaan.
Titans head coach Mark Boucher called-up Klaasen as a replacement in their semi-final fixture with the Titans opting to bat first in Centurion.
READ: Shamsi knocking on Proteas door
Tabraiz Shamsi's heroics helped book the Titans their ticket to the final with an emphatic eight-wicket win over the Warriors.
Boucher and his charges will host the Dolphins in the T20 Challenge final at SuperSport Park on Saturday. Play starts at 18:00.