Cape Town - Duan Olivier claimed three wickets as the Knights held the edge following the opening day of their Sunfoil Series encounter against the Titans in Centurion on Thursday.
The young seamer ended day one with 3/45 as the hosts were reduced to 260/6 by the close after winning the toss and batting first at SuperSport Park.
It was a splendid fightback from the visitors, considering the table-topping home side were on 106/1 and 187/2 at stages during the day.
Proteas opener Dean Elgar, playing in his second match of the season, top-scored with 79 (181 balls, 10 fours, 1 six).
He shared key stands of 90 for the first wicket with Heino Kuhn (45), who went past 500 runs for the season, and 81 for the third wicket with Theunis de Bruyn (40).
But once the three fell, it paved the way for the Knights to stage a fight back.
Malusi Siboto (1/39), Shadley van Schalkwyk (1/43) and Mbulelo Budaza (1/45) were the other bowlers that got into the wickets column to give the Central Franchise the edge.