New York - Stan Wawrinka reached the US Open semi-finals on Wednesday with a 6-4, 6-4, 6-0 rout of South Africa's Kevin Anderson to set-up a semi-final clash with compatriot Roger Federer.
French Open champion Wawrinka booked a spot in his second US Open last-four match, having also reached the same stage in 2013.
Anderson, the 15th seed and playing in his first Grand Slam quarter-final, had knocked out third seed Andy Murray in the previous round.
That effort seemed to take its toll as he committed 42 unforced errors and carved out just a single break point against the fifth-seeded Wawrinka, who romped to victory in just 107 minutes.
The result shattered 29-year-old Anderson's hopes of becoming the first South African in the semi-finals in New York since Johan Kriek in 1980.
Federer beat Frenchman Richard Gasquet 6-3, 6-3, 6-1 in the later quarter-final clash.
Federer has a 16-3 career lead over Wawrinka, his Davis Cup-winning teammate, but Wawrinka won their last clash at the French Open quarter-finals this year.
Anderson had beaten Wawrinka the last four times they played but he was horribly out of sorts on Wednesday, dropping serve in the seventh game of the first set and ninth of the second.
The third set was all over in 25 minutes with Anderson winning just five points.
US Open results on Wednesday, the 10th day of the 2015 tournament at Flushing Meadows (x denotes seeded player):
Stan Wawrinka (SUI x5) bt Kevin Anderson (RSA x15) 6-4, 6-4, 6-0
Roger Federer (SUI x2) bt Richard Gasquet (FRA x12) 6-3, 6-3, 6-1
Flavia Pennetta (ITA x26) bt Petra Kvitova (CZE x5) 4-6, 6-4, 6-2
Simona Halep (ROM x2) bt Victoria Azarenka (BLR x20) 6-3, 4-6, 6-4
Dominic Inglot/Robert Lindstedt (GBR/SWE) bt Rohan Bopanna/Florin Mergea (IND/ROM x6) 7-6 (7/2), 6-3
Steve Johnson/Sam Querrey (USA/USA) bt Leonardo Mayer/Joao Sousa (POR) 6-3, 6-4
Martina Hingis/Sania Mirza (SUI/IND x1) bt Sara Errani/Flavia Pennetta (ITA/ITA x11) 6-4, 6-1
Anna-Lena Groenefeld/Coco Vandeweghe (GER/USA) bt Caroline Garcia/Katarina Srebotnik (FRA/SLO x5) 7-6 (7/5), 7-5
Casey Dellacqua/Yaroslava Shvedova (AUS/KAZ x4) bt Alla Kudryavtseva/Anatasia Pavlyuchenkova (RUS/RUS x12) 6-2, 2-6, 6-3
Bethanie Mattek-Sands/Sam Querrey (USA) bt Andrea Hlavackova/Lukasz Kubot (POL) 6-4, 6-3
Martina Hingis/Leander Paes (SUI/IND x4) bt Yung-Jan Chan/Rohan Bopanna (TPE/IND x2) 6-2, 7-5