Charleston - Australia's Samantha Stosur booked her semi-final spot at the WTA Charleston clay court event with a pair of three-set wins on Friday, ruining the prospect of an all-Williams clash.
Stosur, who turned 28 last Friday, ousted world No 87 Venus Williams with a 6-3, 4-6, 6-3 win in the quarter-finals to set up a semi-final showdown against Serena Williams.
Stosur, of the Golf Coast, was leading Galina Voskoboeva 4-2 in the first set on Thursday when the match was halted because of rain. First up on Friday on center court, No 2 seed Stosur finished off Voskoboeva with a 6-3, 4-6, 6-2 third-round win. She was back on court less than two hours later to face Venus.
"I don't think it was the end of the world to get out there and play this morning," Stosur said. "Today was very different than what we've been playing in, so it was good to get used to the conditions. I would have preferred not to play two three set matches, but nevertheless, I'm happy to be through."
Serena reached the semi-finals on Friday when injury-cursed Sabine Lisicki quit their last-eight clash in floods of tears.
The American fifth seed was 5-1 ahead in the first set when Lisicki -- whose career went into a tailspin in 2010 when an injury left her barely able to walk -- retired after falling and hurting her ankle.
Stosur posted her first career win over Venus after losing four straight -- all in straight sets, including three on clay.
Stosur hammered four aces, won 61 percent of her first-serve points and saved eight-of-12 break point opportunities.
"It's only one win compared to I don't know how many times she's beaten me, five or six, but of course I'm very, very happy to have beaten Venus now," Stosur said. "It's always a good challenge coming up against the players you've never beaten, and I've always struggled against her game, but thankfully I was able to turn it around."
Seven-time Grand Slam winner Venus, who was playing on a wild card invitation, made five double faults and won just 42 percent of her second-serve points. The 31-year-old Venus is trying to rebuild a ranking dented by a lengthy injury and illness layoff.
It has only happened eight times that a WTA player has defeated both Williams at the same tournament: 1998 Sydney (Arantxa Sanchez-Vicario), 1999 Sydney (Steffi Graf), 2001 Australian Open (Martina Hingis), 2002 WTA Championships (Kim Clijsters), 2004 Los Angeles (Lindsay Davenport), 2007 US Open (Justine Henin), 2009 US Open (Clijsters) and 2010 Rome on clay (Jelena Jankovic).
Serena won warm applause from the crowd as she tried to console the stricken Lisicki.
"I totally get it," said Williams, who has endured her own battles with injury and illness, when asked if she sympathised with the German.
"I just told her it would be all right. I'm in an emotional time in my life, so I told her, 'Don't cry, because you're going to make me cry,' and I was like, my eyes are getting watery.
"I'm always crying. But it's not the French Open now. At least it happened earlier and you can recover. It's okay. I've been through those injuries, and it sucks. It really, really sucks."
Serena posted her second career win over Lisicki, following a 6-1, 6-2 rout last year in the semis of the Stanford event.
In the other quarter-final contest, Czech ninth seed Lucie Safarova surprised fourth seeded Vera Zvonareva of Russia 6-3, 6-3 in an 85-minute match.
Zvonareva, a two-time finalist here in 2010 and 2008, also won their only previous match.
In the night match, 14th seeded Polona Hercog easily defeated No 13 Nadia Petrova of Russia 6-1, 6-2 to advance to the semis where she will face Safarova on Saturday.