Madrid - World No 4 four Andy Murray crashed out of the Madrid Open when he was beaten 6-4 6-2 by unseeded Brazilian Thomaz Bellucci in the third round on Thursday.
Briton Murray, who is returning from an elbow injury that prevented him playing at last month's Barcelona Open, had his serve broken once in the first set and twice in the second by the stylish left-hander in the pair's first meeting.
Bellucci, ranked 36, saved all three break points he faced and sealed victory on his first match point when Murray netted a backhand.
He will play Tomas Berdych on Friday for a place in the last four of the clay event after the Czech seventh seed beat unseeded Argentine Juan Monaco 7-5 6-3.
Results on the sixth day of the ATP/WTA Madrid Masters (x denotes seeding):
Men
Third round
Rafael Nadal (ESP x1) bt Juan Martin Del Potro (ARG) - walkover
Roger Federer (SUI x3) bt Xavier Malisse (BEL) 6-4, 6-3
Tomas Berdych (CZE x7) bt Juan Monaco (ARG) 7-5, 6-3
Thomaz Belluci (BRA) bt Andy Murray (GBR x4) 6-4, 6-2
Novak Djokovic (SRB x2) bt Guillermo Garcia-Lopez (ESP) 6-1, 6-2
Women
Third Round
Julia Goerges (GER) bt Caroline Wozniacki (DEN x1) 6-4, 1-6, 6-3
Li Na (CHN x6) bt Roberta Vinci (ITA) 2-6, 6-2, 6-1
Victoria Azarenka (BLR x4) bt Arantxa Parra Santonja (ESP) 6-0, 6-3
Anastasia Pavlyuchenkova (RUS) bt Samantha Stosur (AUS x5) 7-6 (7/4), 6-3
Lucie Safarova (CZE) bt Jarmila Gajdosova (AUS) 6-3, 6-3
Bethanie Mattek-Sands (USA) bt Francesca Schiavone (ITA x3) 7-6 (7/5), 6-3