Paris - Ivo Karlovic of Croatia has stopped playing because of an injury after losing the first set of his third-round French Open match on Saturday against 19th-seeded Kevin Anderson of South Africa.
Karlovic, at 35 the oldest man left in the field, dropped three games in a row to lose the opening set 6-3.
He then was treated by a trainer, who massaged the 6-foot-11 (2.11m) Karlovic's back.
Anderson moves into the fourth round at Roland Garros for the second year in a row, matching his best showing at any Grand Slam tournament.
In 2013, he became the first man from South Africa to reach the round of 16 in Paris since Wayne Ferreira in 1996.
He will face David Ferrer in the next round, the same player who eliminated him at the same stage during last year's tournament.
Ferrer extended his perfect career mark against Andreas Seppi, improving to 7-0 against Seppi, 15-0 in sets, by beating the 32nd-seeded Italian 6-2, 7-6 (2), 6-3.
In 2013 at Roland Garros, Ferrer reached his first Grand Slam final before losing to Rafael Nadal.
Seppi is 1-50 in his last 51 matches against opponents ranked in the top 10.
Men
Third round
Dusan Lajovic (SRB) bt Jack Sock (USA) 6-4, 7-5, 6-3
Kevin Anderson (RSA x19) bt Ivo Karlovic (CRO) 6-3 - retired
David Ferrer (ESP x5) bt Andreas Seppi (ITA x32) 6-2, 7-6 (7/2), 6-3
Marcel Granollers (ESP) bt Martin Klizan (SVK) 6-7 (5/7), 6-2, 7-6 (7/4), 7-5
Women
Third round
Svetlana Kuznetsova (RUS x27) bt Petra Kvitova (CZE x5) 6-7 (3/7), 6-1, 9-7
Lucie Safarova (CZE x23) bt Ana Ivanovic (SRB x11) 6-3, 6-3
Sloane Stephens (USA x15) bt Ekaterina Makarova (RUS x22) 6-3, 6-4
Simona Halep (ROM x4) bt Mara Teresa Torr Flor (ESP) 6-3, 6-0
Jelena Jankovic (SRB x6) bt Sorana Cirstea (ROM x26) 6-1, 6-2
Sara Errani (ITA x10) bt Julia Glushko (ISR) 6-0, 6-1