Rome - World number one Rafael Nadal dug deep to maintain his chances of defending his Rome Masters title after a gutsy come-from-behind 1-6, 6-3, 7-5 win over Andy Murray in the quarter-finals on Friday.
Murray had won only five of his last 18 matches against Nadal but held the bragging rights from their last two - a walkover win in the semis of the Miami Masters and victory in the final of the Tokyo Open in 2011, both hardcourt events.
And despite doubts lingering over the Scot's form following an absence from the tour due to back surgery at the start of the year, Murray produced a stunning performance at the Foro Italico to underline his form ahead of the French Open later this month.
The Scot raced to a 6-1 win in the opening set, leaving clay-court kind Nadal to tinker with tactics in the second set in a bid to pull level.
In a much tighter third set, Nadal maintained his momentum by winning three breaks to two for Murray.
The Spaniard broke in the first game, only for Murray to break back immediately in a second game which saw the Scot pull off a stunning pull-back shot which stunned Nadal and had the crowd in raptures.
That gave Murray some momentum of his own and the British number one held serve to go 2-1 in front.
Both players held serve in the next two games and with the score at 3-2 Murray raced to triple break point to break again and take a two-game lead after Nadal netted a return from a powerful serve.
Sensing defeat, the Spaniard upped his game and broke back to level at 4-4. Both players held serve over the next two games, but Nadal made the difference when he raced to triple break point in the 11th game before breaking for a third time in the set for a 6-5 lead and then serving out for the win.
Nadal will now meet Bulgarian Grigor Dimitrov in the semis on Saturday, when number two seed Novak Djokovic faces Canada's Milos Raonic.
Djokovic ousted David Ferrer 7-5, 4-6, 6-3 while Raonic claimed his last-four spot with a commanding 6-3, 5-7, 6-2 quarter-final win over Frenchman Jeremy Chardy.
Italy's number 10 seed Sara Errani, meanwhile, stunned China's number two seed Li Na 6-3, 4-6, 6-2 to make the semis for the second consecutive year.
She is on course to become the first Italian woman since Raffaella Reggi 29 years ago to win the tournament and next meets Serbian sixth seed Jelena Jankovic after she accounted for Agnieszka Radwanska, the third seed from Poland, 6-4, 6-4.
Errani and Jankovic were joined in the last four by Ana Ivanovic, although the Serbian 11th seed had to dig deep throughout a thrilling encounter with Carla Suarez Navarro before finally beating the Spaniard, seeded 13, 6-4, 3-6, 6-4.
Ivanovic will next meet Serena Williams after she annihilated unseeded Chinese player Zhang Shuai 6-1, 6-3. Ivanovic knows she faces a tough task.
Collated results on Friday from the fifth day of the WTA/ATP Rome Masters tournament (x denotes seeds):
Rafael Nadal (ESP x1) bt Andy Murray (GBR x7) 1-6, 6-3, 7-5
Novak Djokovic (SRB x2) bt David Ferrer (ESP x5) 7-5, 4-6, 6-3
Grigor Dimitrov (BUL x12) bt Tommy Haas (GER x15) 6-2, ret'd
Milos Raonic (CAN x8) bt Jeremy Chardy (FRA) 6-3, 5-7, 6-2
Serena Williams (USA x1) bt Shuai Zhang (CHN) 6-1, 6-3
Jelena Jankovic (SRB x6) bt Agnieszka Radwanska (POL x3) 6-4, 6-4
Sara Errani (ITA x10) bt Li Na (CHN x2) 6-3, 4-6, 6-2
Ana Ivanovic (SRB x11) bt Carla Suarez Navarro (ESP x13) 6-4, 3-6, 6-4