Miami - Britain's Andy Murray won his 500th career victory on Tuesday, defeating South Africa's Kevin Anderson 6-4, 3-6, 6-3 to reach the ATP and WTA Miami Open quarter-finals.
The third-seeded Scotsman, who holds two Grand Slam titles, needed his best effort against his 17th-ranked rival.
Murray, who has won four of five matches against Anderson, improved his career match record to 500 triumphs and 155 defeats with 31 titles, including the 2012 US Open and 2013 Wimbledon crowns.
A brief post-match ceremony paid tribute to Murray's achievement.
Murray is the first British man, the ninth active player and the 46th man in the post-1968 Open Era to achieve the 500-win plateau.
Next up for Murray will be Austrian Dominic Thiem, who defeated Frenchman Adrian Mannarino 7-6 (7/5), 4-6, 7-5.
Also advancing was Japanese fourth seed Kei Nishikori, who dispatched Belgium's David Goffin 6-1, 6-2. That will push Nishikori to fourth in the world rankings with Spain's Rafael Nadal falling to fifth.
Nishikori next will face the winner of a later match between Canada's Milos Raonic and American John Isner.
Another quarter-final was set as Czech eighth seed Tomas Berdych advanced thanks to a mid-match withdrawal from France's injury-hit Gael Monfils. Berdych won 6-3, 3-2 when his opponent stopped a game after falling heavily on his right hip. Monfils has now withdrawn 15 times in his career.
"In the end I feel sorry for Gael. That's not the ideal way to finish up the match," Berdych said. "But in the end, I'm through. That's what matters. That's what counts.
"I'm happy with the win. Really it's not the way that you want to finish the match, but that's how it is. So we need to move on and just go for the next one."
Berdych will take on Argentina's Juan Monaco, a 6-3, 6-3 winner over Fernando Verdasco. Monaco will be playing in the last eight at the ATP Masters level for the first time in three years.
Spanish sixth seed David Ferrer beat French 12th seed Gilles Simon 7-6 (7-5), 6-0.
On the women's side, German ninth seed Andrea Petkovic ousted Czech 14th seed Karolina Pliskova 6-4, 6-2.Results on Tuesday from the eighth day of the ATP and WTA Miami Open(x denotes seeded player):
Tomas Berdych (CZE x8) bt Gael Monfils (FRA x17) 6-3, 3-2, retired, right hip injury
Dominic Thiem (AUT) bt Adrian Mannarino (FRA x28) 7-6 (7/5), 4-6, 7-5
Juan Monaco (ARG) bt Fernando Verdasco (ESP x29) 6-3, 6-3
Andy Murray (GBR x3) bt Kevin Anderson (RSA x15) 6-4, 3-6, 6-4
David Ferrer (ESP x6) bt Gilles Simon (FRA x12) 7-6 (7/5), 6-0
Kei Nishikori (JPN x4) bt David Goffin (BEL x18) 6-1, 6-2
Novak Djokovic (SRB x1) bt Alexandr Dolgopolov (UKR) 6-7 (3/7), 7-5, 6-0
John Isner (USA x22) bt Milos Raonic (CAN x5) 6-7 (3/7), 7-6 (8/6), 7-6 (7/5)
Andrea Petkovic (GER x9) bt Karolina Pliskova (CZE x14) 6-4, 6-2
Carla Suarez Navarro (ESP x12) bt Venus Williams (USA x16) 0-6, 6-1, 7-5