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"I do think using technology in sport is a bonus," Cameron said at a summit of world leaders in Toronto. "It may be that's something in football we could have a look at."
England midfielder Frank Lampard also called for the World Cup to adopt technology to avoid errors similar to the one that saw his goal disallowed during England's 4-1 defeat to Germany on Sunday.
Cameron took time out at the Group of 20 (G20) summit to watch the second half of the England-Germany match with German Chancellor Angela Merkel.
Cameron said he was "deeply disappointed" with his country's loss, but admitted the 4-1 loss suggested even a poor referee call could not have changed England's fortunes.
"The Germans played very well. We have some questions to ask," he said. "With a score like that, we can't truly say we were robbed. We were beaten."
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