Cape Town - Bidvest Wits suffered a 1-0 defeat to Al Ahly in their CAF Champions League first-leg tie at the Al Salam Stadium in Cairo on Saturday.
It was a tight opening to the contest although the hosts thought they had taken the lead in the 20th minute but it was chalked off for an infringement.
In the 31st minute Wits goalkeeper Moeneeb Josephs had to be sharp to palm away a cross.
After the break, Al Ahly threatened again through Amr Gamal as he hit the woodwork from a powerful strike.
The Red Devils would eventually take the lead after continuing to pressure Wits in the 56th minute when Ahmed Hegazi headed home from a corner.
The Clever Boys were relying on efforts from range but didn't really look like scoring, and in the 66th minute Josephs produced another good save to make sure Al Ahly did not double their lead.
Despite applying some pressure in the final stages of the game, Gavin Hunt's side were unable to really carve out any openings and it ended 1-0 to the Egyptian giants.
Second-leg will be played on March 19 at Bidvest Stadium.
Kick off is at 15:30.