Cape Town - Cape Town City and Bidvest Wits will meet for an Absa Premiership title ‘six-pointer’ at Cape Town Stadium.
City claimed a fourth win from their last five league matches when they beat Platinum Stars 4-2 away on April 13.
The Cape Town side has claimed 23 points from 11 home matches this season.
The Citizens are placed first on the Absa Premiership log with 45 points from 23 matches.
Wits claimed a third win from their last four league matches when they defeated Golden Arrows 3-0 at home on April 11.
The Johannesburg side has claimed 19 points from 11 away matches this season.
The Clever Boys are placed third on the Absa Premiership log with 44 points from 21 matches.
In head-to-head stats, City and Wits have met in just one previous top flight league match.
That encounter took place earlier this season, with the Citizens claiming a 3-2 away win in Johannesburg.
Kick off is at 19:30 on Wednesday evening.