The Buccaneers travel to Pretoria to meet the Brazilians in a top-of-the-table PSL clash at Loftus Stadium this week.
Pirates have not lost to Sundowns in six previous meetings dating back to May 2010 when the latter claimed a 3-1 victory in the Nedbank Cup, but Segolela tells Football411.com past results will count for little come match day.
"Sundowns is a dangerous team and it doesn't matter how many times they have lost to us," Segolela told this site.
"The fact is Sundowns are top of the log and it is not by mistake that they are the leaders in the league so we have to respect that, but on the other hand this is a great opportunity for us to cut their lead to one point and I believe we are capable of beating Sundowns, but we shouldn't rely too much on what happened in the past.
"I just hope me and my team will be calm," he cautioned.
"I hope our supporters will come in numbers, because this is one clash where you need your fans because the reality is the destiny of the league title depends a lot on this game."
Meanwhile, in-form striker Benni McCarthy says he hopes it would be a spectacle for the fans.
"I just hope it will be a thriller for those with the tickets and also, I hope it will be one of those exciting games with lots of goals. Hopefully, the best team will win," McCarthy said.
Downs currently top the table with 40 points from 20 matches, while the Bucs are second with 36 points from the same number of matches.