Cape Town - Orlando Pirates and SuperSport United will both have the chance to make a big statement in the Premiership when they meet at the Peter Mokaba Stadium.
The opening weekend of the new campaign saw draws for both defending champions Kaizer Chiefs and 2014/15 runners-up Mamelodi Sundowns, with Bidvest Wits the only one of last season's top three to register a victory.
That means either the Buccaneers and Matsatsantsa can get an early jump on their title rivals as both look to start the campaign on a high note.
The impetus may be with Pirates heading into the clash, with Eric Tinkler's men flying high in the CAF Confederations Cup, where Saturday's 2-0 win over CS Sfaxien took the Soweto giants back top of Group B and virtually assured of a place in the semi-finals.
However, they entered this past weekend's continental encounter on the back of a demoralising 1-0 loss to Ajax Cape Town in the MTN8 quarter-finals, hinting at another term of inconsistency for the Sea Robbers.
SuperSport, meanwhile, have plenty to improve on from last season after managing only a sixth-placed finish in the league, while their subsequent adventure in this year's MTN8 came to an end at the first hurdle after going down to Wits 3-1 in extra-time last week.
On the team front, there could be a host of debuts for SuperSport, with defenders Bongani Khumalo and Michael Boxall, as well as striker Fagrie Lakay, all having been signed by Gordon Igesund in the off-season.
Meanwhile, Edwin Gyimah could make his first Premiership appearance for Pirates against his former employers, but Thamsanqa Gabuza is rated as doubtful as he continues to recover from injury.
Kick-off is at 19:30.