The Bafana Bafana star, who is currently sidelined with an ankle injury, has received a wealth of interest in his services following the World Cup.
Football365.co.za broke the news that Khumalo had earned a trial with English Premier League side Tottenham Hotspur, while Scottish giants Rangers have also made their admiration of the 23-year-old clear.
"I do not have much time (to find a replacement) but it looks like Khumalo might leave," Hunt said at the launch of the 2010/11 season in Maropeng on Monday night.
"But nothing has been confirmed."
Khumalo has been touted as a future Bafana captain by former coach Carlos Alberto Parreira and will be a major loss to United. But Hunt is renowned for dealing with the departure of key players and will be odds on to lead Matsatsantsa to yet another league crown.