Cape Town - Chippa United will look to bounce back from midweek defeat in the Absa Premiership when they host Polokwane City at Nelson Mandela Bay Stadium.
Chippa suffered their third loss of the season when they were beaten 3-2 at Platinum Stars on September 22.
The Eastern Cape side has claimed four points from two home matches so far this season.
The Chilli Boys are placed 13th on the Absa Premiership log with four points from five matches.
Polokwane saw their winless streak extended to four matches when they were held 0-0 at home by Orlando Pirates on September 22.
The Limpopo side has lost both of their two away matches so far this season.
Rise and Shine are placed 11th on the Absa Premiership log with five points from as many matches.
In head-to-head stats, Chippa and Polokwane have met in just two previous top flight matches.
Both of those encounters took place last season, with Rise and Shine claiming a 3-1 home victory in the first half of the season.
The return game in the Eastern Cape saw the Chilli Boys hold out for a 1-1 draw.
Kick-off is at 20:00 on September 25.