Johannesburg - Kaizer Chiefs edged a gritty Wits side with a 2-1 victory in their Premiership encounter in Nasrec on Saturday evening.
Amakhosi piled on the pressure in the first half but were unable to find an early breakthrough.
Siphiwe Tshabalala's attempt in the 17th minute was parried away by Wits goalkeeper Moeneeb Josephs, and Siyabonga Nkosi thundered an effort across face of goal from the rebound.
Kingston Nkhatha had an opportunity on the half-hour mark but he directed his shot over the bar from close range.
With five minutes left in the first half, Josephs did well to save an attempt from Bernard Parker to keep the sides level at the half-time break.
Nkhatha made up for it, however, when he struck four minutes after the interval, climbing high to reach a cross from Parker on the right and netting a header to put the home side in front.
On the hour mark, Nkhatha was denied with only the 'keeper to beat when a vulnerable Josephs ran out and put his body on the line to block the ball.
Wits hit back in the 66th minute when veteran Matthew Booth produced a clever flick which found Ryan Chapman, who buried the ball in the back of the net, just minutes after coming on as a substitute.
Chiefs maintained their composure, however, and drew ahead again with five minutes left when Lehlohonolo Majoro smashed his header against the post, with a fumbling Josephs knocking the ball in off the rebound.
Josephs pulled off a great save to keep out Majoro in injury time, but Amakhosi had done enough to grab three valuable points, handing high-flying Wits their first loss in four games.