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Montevideo - Argentina and Brazil reignited their 2018 World Cup qualifying campaigns with important victories on Tuesday as Copa America champions Chile crashed to defeat in their grudge match with Uruguay.
Two-time World Cup winners Argentina - who had taken just two points from their first three matches - claimed their first win, downing Colombia 1-0 in Barranquilla thanks to a first-half goal from Lucas Biglia.
Brazil meanwhile produced their best performance of the qualifying campaign to date with a 3-0 defeat of Peru in Salvador.
Bayern Munich star Douglas Costa scored one goal and created two others as Brazil swept aside the challenge of the Copa America semi-finalists.
In Montevideo, Uruguay gained revenge for their stormy Copa America quarter-final defeat to Chile earlier this year with a 3-0 win.
The victory pushed Uruguay up to second place in the standings with nine points from four games, three points adrift of surprise early pacesetters Ecuador, who made it four wins out of four on Tuesday with a 3-1 win over Venezuela.
Brazil's victory over Peru left them in third place with seven points, ahead of Paraguay and Chile on goal difference.
Argentina's win in Colombia lifted them to sixth, just outside the top five qualifying spots.
