Frankfurt - Borussia Dortmund's relegation worries mounted on Wednesday after Jurgen Klopp's side lost 1-0 at home to 10-man Augsburg.
Juergen Klopp's team remained bottom of the table, two points behind Hertha Berlin, which lost 1-0 to Bayer Leverkusen.
Dortmund, twice champion and twice runner-up in the past four seasons, has now failed to score in two matches since the season resumed over the weekend.
More worryingly, it hardly created any chances even after Augsburg was reduced to 10 men in the 64th minute when Christoph Janker was sent off. Raul Bobadilla scored the winner for Augsburg in the 50th.
Augsburg moves into fourth place as a result of the win and is in a Champions League qualifying place.
Elsewhere, Hamburger SV won 3-0 in Paderborn, Werder Bremen beat Hoffenheim 2-1 and Cologne and Stuttgart drew 0-0.
Dortmund was booed off the field by its fans after losing its 11th match of the season, four of them at home.
"It hurts, no doubt," Klopp said. "We are doing everything wrong at the moment. We are not making anything of our chances."
Augsburg's goal came after four Dortmund defenders failed to stop Halil Altintop and the loose ball fell kindly to Bobadilla, who slotted home.
Janker was sent off for downing Pierre-Emerick Aubameyang after which the visitors put all its men behind the ball as they looked to preserve their lead.
Dortmund found no way through until stoppage time, but Ciro Immobile missed from close range.