Southampton - Crystal Palace's revival in the Premier League was ended after conceding two late goals in a 3-1 loss at Southampton on Wednesday, plunging the team back into relegation trouble.
After beating first-place Chelsea 2-1 on Saturday for a fourth straight win, Palace took the lead against Southampton through Christian Benteke in the 31st minute.
But Nathan Redmond equalized in the 45th, before Japan defender Maya Yoshida's tap-in put Southampton ahead in the 84th and James Ward-Prowse added a third for the home side a minute later.
Palace dropped to within three points of the relegation zone and has a tough eight-game run-in that includes matches against Arsenal, Liverpool, Tottenham, Manchester City and Manchester United.
Southampton climbed from 13th to ninth place.
It doesn't get any easier for the Eagles who next host London rivals Arsenal in an English Premiership clash on Monday evening that both sides cannot afford to lose with Arsenal chasing a Champions League spot.
Kick off is at 21:00.