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London - Premier League champions Manchester City will begin their title defence away to Arsenal on the weekend of August 11-12, the English Premier League announced Thursday as it unveiled the fixtures for the 2018/19 season.
The match will also be new Arsenal manager Unai Emery's first in English football's top flight.
The exact date of the game will be confirmed when television broadcasting schedules are drawn up.
City amassed 100 points and scored 106 goals while finishing 19 points clear of second-placed Manchester United in the 2017/18 season.
Following the Arsenal game, City do not face another top-six team until they are away to Liverpool - who beat Pep Guardiola's men in the quarter-finals of the Champions League last season - in October.
In between those two eye-catching fixtures, City will play the newly-promoted trio of Wolverhampton Wanderers, Cardiff City and Fulham, as well as last year's promoted teams Huddersfield, Newcastle and Brighton.
Manchester United begin their league campaign at home to Leicester City and face a potentially tricky encounter in their third game when Tottenham Hotspur come to Old Trafford.
Jose Mourinho's side face Brighton and Hove Albion, Burnley, Watford and Wolves in other early-season games.
Liverpool, the losing Champions League finalists, appear to have the toughest start of any of the likely title-contenders.
They begin their Premier League season at home to West Ham before facing Crystal Palace, Brighton and Leicester.
Tottenham have until Friday to decide if they will still be playing home games at Wembley this season.
Spurs made the journey across north London to the national stadium last term while their successor ground to White Hart Lane was being built.
That work has still to be completed, with Premier League chiefs giving Spurs an away start at Newcastle.
Arsenal have a tough start under new Spanish boss Emery, who has the daunting task of succeeding the long-serving Arsene Wenger, with the Gunners away to Chelsea after facing Manchester City
Chelsea begin the league campaign away to Huddersfield and, after their all-London clash against Arsenal, face Newcastle, Bournemouth, Cardiff, West Ham, Liverpool and Southampton.
None of the promoted sides have been given a horror run of games against leading clubs at the start of the season, although they will each face at least one of the big six in their opening four fixtures.
Championship-winners Wolves begin their return to the Premier League at home to Everton before matches away to Leicester and West Ham bookend the visit of Manchester City to Molineux.
Cardiff start at Bournemouth while Fulham, who secured their place in the top flight via a Wembley playoff final win over Aston Villa start the league season at home to Crystal Palace.
The final round of Premier League fixtures, scheduled for May 12, will see Manchester City away to Brighton, while Manchester United and Liverpool are at home to Cardiff and Wolves respectively.
Premier League 2018/19 fixtures in full:
Saturday, 11 August, 2018
Arsenal v Man City
AFC Bournemouth v Cardiff City
Fulham v Crystal Palace
Huddersfield Town v Chelsea
Liverpool v West Ham
Man Utd v Leicester City
Newcastle United v Spurs
Southampton v Burnley
Watford v Brighton
Wolves v Everton
Saturday, 18 August, 2018
Brighton v Man Utd
Burnley v Watford
Cardiff City v Newcastle United
Chelsea v Arsenal
Crystal Palace v Liverpool
Everton v Southampton
Leicester City v Wolves
Man City v Huddersfield Town
Spurs v Fulham
West Ham v AFC Bournemouth
Saturday, 25 August 2018
Arsenal v West Ham
AFC Bournemouth v Everton
Fulham v Burnley
Huddersfield Town v Cardiff City
Liverpool v Brighton
Man Utd v Spurs
Newcastle United v Chelsea
Southampton v Leicester City
Watford v Crystal Palace
Wolves v Man City
Saturday, 1 September 2018
Brighton v Fulham
Burnley v Man Utd
Cardiff City v Arsenal
Chelsea v AFC Bournemouth
Crystal Palace v Southampton
Everton v Huddersfield Town
Leicester City v Liverpool
Man City v Newcastle United
Watford v Spurs
West Ham v Wolves
Saturday, 15 September 2018
AFC Bournemouth v Leicester City
Chelsea v Cardiff City
Everton v West Ham
Huddersfield Town v Crystal Palace
Man City v Fulham
Newcastle United v Arsenal
Southampton v Brighton
Spurs v Liverpool
Watford v Man Utd
Wolves v Burnley
Saturday, 22 September 2018
Arsenal v Everton
Brighton v Spurs
Burnley v AFC Bournemouth
Cardiff City v Man City
Crystal Palace v Newcastle United
Fulham v Watford
Leicester City v Huddersfield Town
Liverpool v Southampton
Man Utd v Wolves
West Ham v Chelsea
Saturday, 29 September 2018
Arsenal v Watford
AFC Bournemouth v Crystal Palace
Cardiff City v Burnley
Chelsea v Liverpool
Everton v Fulham
Huddersfield Town v Spurs
Man City v Brighton
Newcastle United v Leicester City
West Ham v Man Utd
Wolves v Southampton
Saturday, 6 October 2018
Brighton v West Ham
Burnley v Huddersfield Town
Crystal Palace v Wolves
Fulham v Arsenal
Leicester City v Everton
Liverpool v Man City
Man Utd v Newcastle United
Southampton v Chelsea
Spurs v Cardiff City
Watford v AFC Bournemouth
Saturday, 20 October 2018
Arsenal v Leicester City
AFC Bournemouth v Southampton
Cardiff City v Fulham
Chelsea v Man Utd
Everton v Crystal Palace
Huddersfield Town v Liverpool
Man City v Burnley
Newcastle United v Brighton
West Ham v Spurs
Wolves v Watford
Saturday, 27 October 2018
Brighton v Wolves
Burnley v Chelsea
Crystal Palace v Arsenal
Fulham v AFC Bournemouth
Leicester City v West Ham
Liverpool v Cardiff City
Man Utd v Everton
Southampton v Newcastle United
Spurs v Man City
Watford v Huddersfield Town
Saturday, 3 November 2018
Arsenal v Liverpool
AFC Bournemouth v Man Utd
Cardiff City v Leicester City
Chelsea v Crystal Palace
Everton v Brighton
Huddersfield Town v Fulham
Man City v Southampton
Newcastle United v Watford
West Ham v Burnley
Wolves v Spurs
Saturday, 10 November 2018
Arsenal v Wolves
Cardiff City v Brighton
Chelsea v Everton
Crystal Palace v Spurs
Huddersfield Town v West Ham
Leicester City v Burnley
Liverpool v Fulham
Man City v Man Utd
Newcastle United v AFC Bournemouth
Southampton v Watford
Saturday, 24 November 2018
AFC Bournemouth v Arsenal
Brighton v Leicester City
Burnley v Newcastle United
Everton v Cardiff City
Fulham v Southampton
Man Utd v Crystal Palace
Spurs v Chelsea
Watford v Liverpool
West Ham v Man City
Wolves v Huddersfield Town
Saturday, 1 December 2018
Arsenal v Spurs
Cardiff City v Wolves
Chelsea v Fulham
Crystal Palace v Burnley
Huddersfield Town v Brighton
Leicester City v Watford
Liverpool v Everton
Man City v AFC Bournemouth
Newcastle United v West Ham
Southampton v Man Utd
Tuesday, 4 December 2018
AFC Bournemouth v Huddersfield Town - 19:45
Brighton v Crystal Palace
Burnley v Liverpool
Fulham v Leicester City
Watford v Man City
West Ham v Cardiff City
Wolves v Chelsea
Man Utd v Arsenal
Wednesday, 5 December 2018
19:45 Everton v Newcastle United
20:00 Spurs v Southampton
Saturday, 8 December 2018
Arsenal v Huddersfield Town
AFC Bournemouth v Liverpool
Burnley v Brighton
Cardiff City v Southampton
Chelsea v Man City
Everton v Watford
Leicester City v Spurs
Man Utd v Fulham
Newcastle United v Wolves
West Ham v Crystal Palace
Saturday, 15 December 2018
Brighton v Chelsea
Crystal Palace v Leicester City
Fulham v West Ham
Huddersfield Town v Newcastle United
Liverpool v Man Utd
Man City v Everton
Southampton v Arsenal
Spurs v Burnley
Watford v Cardiff City
Wolves v AFC Bournemouth
Saturday, 22 December 2018
Arsenal v Burnley
AFC Bournemouth v Brighton
Cardiff City v Man Utd
Chelsea v Leicester City
Everton v Spurs
Huddersfield Town v Southampton
Man City v Crystal Palace
Newcastle United v Fulham
West Ham v Watford
Wolves v Liverpool
Saturday, 26 December 2018
Brighton v Arsenal
Burnley v Everton
Crystal Palace v Cardiff City
Fulham v Wolves
Leicester City v Man City
Liverpool v Newcastle United
Man Utd v Huddersfield Town
Southampton v West Ham
Spurs v AFC Bournemouth
Watford v Chelsea
Saturday, 29 December 2018
Brighton v Everton
Burnley v West Ham
Crystal Palace v Chelsea
Fulham v Huddersfield Town
Leicester City v Cardiff City
Liverpool v Arsenal
Man Utd v AFC Bournemouth
Southampton v Man City
Spurs v Wolves
Watford v Newcastle United
Tuesday, 1 January 2019
Arsenal v Fulham
AFC Bournemouth v Watford
Cardiff City v Spurs
Chelsea v Southampton
Everton v Leicester City
Huddersfield Town v Burnley
Man City v Liverpool
Newcastle United v Man Utd
West Ham v Brighton
Wolves v Crystal Palace
Saturday, 12 January 2019
Brighton v Liverpool
Burnley v Fulham
Cardiff City v Huddersfield Town
Chelsea v Newcastle United
Crystal Palace v Watford
Everton v AFC Bournemouth
Leicester City v Southampton
Man City v Wolves
Spurs v Man Utd
West Ham v Arsenal
Saturday, 19 January 2019
Arsenal v Chelsea
AFC Bournemouth v West Ham
Fulham v Spurs
Huddersfield Town v Man City
Liverpool v Crystal Palace
Man Utd v Brighton
Newcastle United v Cardiff City
Southampton v Everton
Watford v Burnley
Wolves v Leicester City
Tuesday, 29 January 2019
19:45 Arsenal v Cardiff City
19:45 AFC Bournemouth v Chelsea
19:45 Fulham v Brighton
19:45 Huddersfield Town v Everton
19:45 Wolves v West Ham
20:00 Man Utd v Burnley
Wednesday, 30 January 2019
19:45 Newcastle United v Man City
19:45 Southampton v Crystal Palace
20:00 Liverpool v Leicester City
20:00 Spurs v Watford
Saturday, 2 February 2019
Brighton v Watford
Burnley v Southampton
Cardiff City v AFC Bournemouth
Chelsea v Huddersfield Town
Crystal Palace v Fulham
Everton v Wolves
Leicester City v Man Utd
Man City v Arsenal
Spurs v Newcastle United
West Ham v Liverpool
Saturday, 9 February 2019
Brighton v Burnley
Crystal Palace v West Ham
Fulham v Man Utd
Huddersfield Town v Arsenal
Liverpool v AFC Bournemouth
Man City v Chelsea
Southampton v Cardiff City
Spurs v Leicester City
Watford v Everton
Wolves v Newcastle United
Saturday, 23 February 2019
Arsenal v Southampton
AFC Bournemouth v Wolves
Burnley v Spurs
Cardiff City v Watford
Chelsea v Brighton
Everton v Man City
Leicester City v Crystal Palace
Man Utd v Liverpool
Newcastle United v Huddersfield Town
West Ham v Fulham
Tuesday, 26 February 2019
19:45 Arsenal v AFC Bournemouth
19:45 Cardiff City v Everton
19:45 Huddersfield Town v Wolves
19:45 Leicester City v Brighton
20:00 Crystal Palace v Man Utd
Wednesday, 27 February 2019
19:45 Chelsea v Spurs
19:45 Newcastle United v Burnley
19:45 Southampton v Fulham
20:00 Liverpool v Watford
20:00 Man City v West Ham
Saturday, 2 March 2019
AFC Bournemouth v Man City
Brighton v Huddersfield Town
Burnley v Crystal Palace
Everton v Liverpool
Fulham v Chelsea
Man Utd v Southampton
Spurs v Arsenal
Watford v Leicester City
West Ham v Newcastle United
Wolves v Cardiff City
Saturday, 9 March 2019
Arsenal v Man Utd
Cardiff City v West Ham
Chelsea v Wolves
Crystal Palace v Brighton
Huddersfield Town v AFC Bournemouth
Leicester City v Fulham
Liverpool v Burnley
Man City v Watford
Newcastle United v Everton
Southampton v Spurs
Saturday, 16 March 2019
AFC Bournemouth v Newcastle United
Brighton v Cardiff City
Burnley v Leicester City
Everton v Chelsea
Fulham v Liverpool
Man Utd v Man City
Spurs v Crystal Palace
Watford v Southampton
West Ham v Huddersfield Town
Wolves v Arsenal
Saturday, 30 March 2019
Arsenal v Newcastle United
Brighton v Southampton
Burnley v Wolves
Cardiff City v Chelsea
Crystal Palace v Huddersfield Town
Fulham v Man City
Leicester City v AFC Bournemouth
Liverpool v Spurs
Man Utd v Watford
West Ham v Everton
Saturday, 6 April 2019
AFC Bournemouth v Burnley
Chelsea v West Ham
Everton v Arsenal
Huddersfield Town v Leicester City
Man City v Cardiff City
Newcastle United v Crystal Palace
Southampton v Liverpool
Spurs v Brighton
Watford v Fulham
Wolves v Man Utd
Saturday, 13 April 2019
Brighton v AFC Bournemouth
Burnley v Cardiff City
Crystal Palace v Man City
Fulham v Everton
Leicester City v Newcastle United
Liverpool v Chelsea
Man Utd v West Ham
Southampton v Wolves
Spurs v Huddersfield Town
Watford v Arsenal
Saturday, 20 April 2019
Arsenal v Crystal Palace
AFC Bournemouth v Fulham
Cardiff City v Liverpool
Chelsea v Burnley
Everton v Man Utd
Huddersfield Town v Watford
Man City v Spurs
Newcastle United v Southampton
West Ham v Leicester City
Wolves v Brighton
Saturday, 27 April 2019
Brighton v Newcastle United
Burnley v Man City
Crystal Palace v Everton
Fulham v Cardiff City
Leicester City v Arsenal
Liverpool v Huddersfield Town
Man Utd v Chelsea
Southampton v AFC Bournemouth
Spurs v West Ham
Watford v Wolves
Saturday, 4 May 2019
Arsenal v Brighton
AFC Bournemouth v Spurs
Cardiff City v Crystal Palace
Chelsea v Watford
Everton v Burnley
Huddersfield Town v Man Utd
Man City v Leicester City
Newcastle United v Liverpool
West Ham v Southampton
Wolves v Fulham
Sunday, 12 May 2019
Brighton v Man City
Burnley v Arsenal
Crystal Palace v AFC Bournemouth
Fulham v Newcastle United
Leicester City v Chelsea
Liverpool v Wolves
Man Utd v Cardiff City
Southampton v Huddersfield Town
Spurs v Everton
Watford v West Ham
