Barcelona - Rubin Kazan failed in their bid to make the last 16 of the Champions League when they lost 2-0 to a second-string Barcelona side in Group D on Tuesday.
Pep Guardiola fielded only two of his regular starting 11 at the Nou Camp and both of the home side's goals were scored by promoted players from the B team.
Andreu Fontas struck in the 51st minute when his left-foot shot was deflected into the net off Vitaly Kaleshin, and Victor Vazquez added a second with a fine curled effort.
FC Copenhagen's 3-1 victory at home to Panathinaikos put the Danes through to the knockout round in second behind Barca, who were already assured of top spot. Rubin, in third, will go into the Europa League.
The home side dominated possession easily enough but lacked penetration in the absence of most of their first choice players.
Barca fans hoping for a show from the club's three Ballon d'Or nominees, Lionel Messi, Andres Iniesta and Xavi, were initially disappointed, with Messi and Iniesta left on the bench and Xavi watching from the stands.
Messi's introduction with just under half an hour to go lifted the crowd and the reigning World Player of the Year managed some trademark weaving runs, although he failed to add to his six goals in the campaign.
Barca finished the group phase with 14 points from six matches, with Copenhagen on 10, Rubin on six and Panathinaikos on two.