According to the Football411.com website, Manyisa was a second-half substitution for Bafana Bafana against the Central African Republic in Saturday's 2-0 victory at Cape Town Stadium.
It was a must-win match for the South Africans, who earned a valuable three points towards their bid to secure qualification for next year's World Cup in Brazil.
"I was happy tonight with Oupa Manyisa when he came on, he put the foot on the ball, he kept it nicely," Igesund told the media following Saturday's match.
"I'm still learning a lot about my players and they are learning a lot about each other as well so this was a very very important game and the nice thing about Sautday's game is that I know what we have to do when we go and play them (CAR) there.
South Africa initially went top of Group A with their recent win, but Ethiopia's triumph over Botswana on Sunday moved them back into pole position.
Nevertheless, Igesund has backed his team to pick up another three points against the Wild Beasts in their own back-yard next time out.
"I'm confident that we can go there and get the points as well because we are better than this team in a lot of departments and we won't get carried away, we will keep working hard and let's hope," he added.