London - Tim Visser is set to miss Scotland's first three Six Nations matches after suffering a hamstring injury while playing for Harlequins.
Visser limped off with a hamstring strain during Harlequins' English Premiership draw with Gloucester last weekend and the 28-year-old wing faces up to eight weeks on the sidelines.
"Tim Visser is expected to be out for between six to eight weeks due to a hamstring injury sustained during Big Game 8," a statement on Harlequins' website announced.
The best case scenario would see Visser only sit out Scotland's opening Six Nations clash with England on February 6 at Murrayfield and Wales' visit to Edinburgh a week later.
But Dutch-born Visser, who has played in 23 Tests, could also miss Scotland's trip to Italy on February 26 if his recovery fails to go smoothly.
His injury comes just a week after head coach Vern Cotter lost the services of Glasgow lock Rob Harley to a thumb injury.